Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

2000 • 3,261 citations

Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer

2000 • 2,981 citations

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

2002 • 2,781 citations

Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma

2005 • 1,613 citations

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

1998 • 1,273 citations

Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity

2004 • 1,213 citations

Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer

1998 • 1,000 citations

Systemic Therapy for Colorectal Cancer

2019 • 872 citations

Adoptive immunotherapy for cancer: building on success

2006 • 848 citations

Mortality Associated With Irinotecan Plus Bolus Fluorouracil/Leucovorin: Summary Findings of an Independent Panel

2001 • 430 citations

Applications of pox virus vectors to vaccination: an update.

1996 • 348 citations

CD28-B7 interactions in T-cell activation

1994 • 315 citations

A Clinical Development Paradigm for Cancer Vaccines and Related Biologics

2006 • 272 citations

Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes.

2001 • 223 citations

Restoration of T-cell homeostasis after T-cell depletion

1997 • 218 citations

Identification of an enhancer agonist cytotoxic T lymphocyte peptide from human carcinoembryonic antigen.

1997 • 210 citations

Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory molecule

2000 • 205 citations

Phase I Study in Cancer Patients of a Replication-Defective Avipox Recombinant Vaccine That Expresses Human Carcinoembryonic Antigen

1999 • 201 citations

Pilot study of a dual gene recombinant avipox vaccine containing both carcinoembryonic antigen (CEA) and B7.1 transgenes in patients with recurrent CEA-expressing adenocarcinomas.

2000 • 154 citations

Carcinoembryonic antigen-based vaccines

2003 • 79 citations

Treatment of Melanoma with 5-Fluorouracil or Dacarbazine In Vitro Sensitizes Cells to Antigen-Specific CTL Lysis through Perforin/Granzyme- and Fas-Mediated Pathways

2004 • 75 citations

Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen.

1997 • 73 citations

Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice

2002 • 71 citations

Dose-comparative monotherapy trials of ZD1839 in previously treated non–small cell lung cancer patients

2003 • 61 citations

Generation of primary tumor-specific CTL in vitro to immunogenic and poorly immunogenic mouse tumors.

1996 • 46 citations

HIV-1 Vaccination Administered Intramuscularly Can Induce Both Systemic and Mucosal T Cell Immunity in HIV-1-Uninfected Individuals

2003 • 39 citations

Strategies for cancer therapy using carcinoembryonic antigen vaccines

2000 • 38 citations

Tumor Vaccination after Allogeneic Bone Marrow Cell Reconstitution of the Nonmyeloablatively Conditioned Tumor-Bearing Murine Host

2003 • 20 citations

Effect of irinotecan on the phenotype of peripheral blood leukocyte populations in patients with metastatic colorectal cancer.

2002 • 18 citations

Induction of HLA-unrestricted and HLA-class-II-restricted cytotoxic T lymphocytes against MUC-1 from patients with colorectal carcinomas using recombinant MUC-1 vaccinia virus

1998 • 12 citations

Forgotten veterinarians. 6. Dr. Snook and murder most foul.

2007 • 4 citations

5-Fluorouracil enhances apoptosis sensitivity of T lymphocytes mediated by CD3ɛ

2004 • 3 citations

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