Galectin-3 Is a Downstream Regulator of Matrix Metalloproteinase-9 Function during Endochondral Bone Formation

Developmental regulation of the growth plate

2003 • 2,694 citations

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

1999 • 2,034 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Reaching a Genetic and Molecular Understanding of Skeletal Development

2002 • 1,564 citations

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1996 • 1,355 citations

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1996 • 855 citations

Expression of galectin-3 modulates T-cell growth and apoptosis.

1996 • 771 citations

Matrix Metalloproteinase 9 and Vascular Endothelial Growth Factor Are Essential for Osteoclast Recruitment into Developing Long Bones

2000 • 589 citations

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

2004 • 581 citations

Maturational disturbance of chondrocytes inCbfa1-deficient mice

1999 • 561 citations

Does adult fracture repair recapitulate embryonic skeletal formation?

1999 • 537 citations

Human Galectin-3 Is a Novel Chemoattractant for Monocytes and Macrophages

2000 • 505 citations

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

2002 • 447 citations

Skeletal defects in VEGF120/120 mice reveal multiple roles for VEGF in skeletogenesis

2002 • 440 citations

Galectin-3 Induces Endothelial Cell Morphogenesis and Angiogenesis

2000 • 438 citations

Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies.

1982 • 428 citations

Targeted Disruption of the Galectin-3 Gene Results in Attenuated Peritoneal Inflammatory Responses

2000 • 425 citations

Galectin-3 : a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family

2000 • 390 citations

Extracellular functions of galectin-3

2002 • 367 citations

Altered fracture repair in the absence of MMP9

2003 • 366 citations

THE VASCULAR CONTRIBUTION TO OSTEOGENESIS

1960 • 336 citations

Galectin-3 and metastasis

2002 • 314 citations

NG2 Proteoglycan Promotes Endothelial Cell Motility and Angiogenesis via Engagement of Galectin-3 and α3β1 Integrin

2004 • 312 citations

L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity

1993 • 263 citations

Galectin-3 Is a Novel Substrate for Human Matrix Metalloproteinases-2 and -9

1994 • 259 citations

THE VASCULAR CONTRIBUTION TO OSTEOGENESIS

1960 • 255 citations

Galectin-3 as a multifunctional protein.

2004 • 236 citations

Galectin-3 overexpression protects from apoptosis by improving cell adhesion properties

2000 • 230 citations

Matrix metalloproteinases are obligatory for the migration of preosteoclasts to the developing marrow cavity of primitive long bones

1995 • 218 citations

Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts

1997 • 213 citations

Secretion of the Baby Hamster Kidney 30-kDa Galactose-Binding Lectin from Polarized and Nonpolarized Cells: A Pathway Independent of the Endoplasmic Reticulum-Golgi Complex

1993 • 201 citations

A molecular analysis of matrix remodeling and angiogenesis during long bone development

2001 • 172 citations

Molecular and Cellular Methods in Developmental Toxicology

2019 • 150 citations

MMP-13 is induced during chondrocyte hypertrophy

2000 • 150 citations

Nucleocytoplasmic lectins

2004 • 144 citations

Visualization of Gene Expression Patterns by In Situ Hybridization

2019 • 134 citations

Collagenase-3 (MMP-13) and Integral Membrane Protein 2a (Itm2a) are Marker Genes of Chondrogenic/Osteoblastic Cells in Bone Formation: Sequential Temporal, and Spatial Expression of Itm2a, Alkaline Phosphatase, MMP-13, and Osteocalcin in the Mouse

2000 • 125 citations

Proteolysis Involving Matrix Metalloproteinase 13 (Collagenase-3) Is Required for Chondrocyte Differentiation That Is Associated with Matrix Mineralization

2002 • 122 citations

Phenotypic and biochemical consequences of collagen X mutations in mice and humans

1998 • 104 citations

Uncoupling of Chondrocyte Death and Vascular Invasion in Mouse Galectin 3 Null Mutant Bones

2001 • 101 citations

Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development

2003 • 88 citations

Expression of Galectin-3 in Skeletal Tissues Is Controlled by Runx2

2003 • 79 citations

Galectin‐3 is expressed in the notochord, developing bones, and skin of the postimplantation mouse embryo

1995 • 75 citations

Galectin-3 surface expression on human adult chondrocytes: a potential substrate for collagenase-3

2004 • 73 citations

Cross‐linking of galectin 3, a galactose‐binding protein of mammalian cells, by tissue‐type transglutaminase

1995 • 72 citations

Galectin-3 Modulates Ureteric Bud Branching in Organ Culture of the Developing Mouse Kidney

2001 • 60 citations

Expression of Mac-2 antigen in the preosteoclast and osteoclast identified in the op/op mouse injected with macrophage colony-stimulating factor

1994 • 55 citations

Cellular and subcellular distribution of galectin-3 in the epiphyseal cartilage and bone of fetal and neonatal mice.

1999 • 49 citations

Expression and regulation of galectin 3 in rat osteoblastic cells

1996 • 45 citations

Stabilization of neurites in cerebellar granule cells by transglutaminase activity: identification of midkine and galectin-3 as substrates

2000 • 44 citations

Cystatin 10, a Novel Chondrocyte-specific Protein, May Promote the Last Steps of the Chondrocyte Differentiation Pathway

2003 • 22 citations