INVOLVEMENT OF ENDOGENOUS INTERLEUKIN-10 AND TUMOR NECROSIS FACTOR-?? IN RENAL ISCHEMIA-REPERFUSION INJURY1,2

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

1991 • 1,880 citations

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

1986 • 1,282 citations

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

1992 • 949 citations

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

1990 • 828 citations

Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia.

1993 • 821 citations

Interleukin 10 protects mice from lethal endotoxemia.

1993 • 807 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.

1993 • 627 citations

Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide.

1993 • 504 citations

The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand.

1997 • 503 citations

Interleukin‐10 inhibits B7 and intercellular adhesion molecule‐1 expression on human monocytes

1994 • 396 citations

Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.

1992 • 383 citations

Cytokine mRNA expression in postischemic/reperfused myocardium.

1995 • 375 citations

Improved method for quantification of tissue PMN accumulation measured by myeloperoxidase activity

1990 • 356 citations

The role of cytokine networks in the local liver injury following hepatic ischemia/reperfusion in the rat

1996 • 312 citations

Interleukin‐10 controls interferon‐γ and tumor necrosis factor production during experimental endotoxemia

1994 • 306 citations

Outcome of transplantation of non-heart-beating donor kidneys

1995 • 287 citations

Differential regulatory effects of adenosine on cytokine release by activated human monocytes.

1994 • 287 citations

Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats.

1997 • 280 citations

Concomitant cortical expression of TNF-α and IL-1β mRNAs follows early response gene expression in transient focal ischemia

1994 • 278 citations

Tumor necrosis factor induces glomerular damage in the rabbit.

1989 • 244 citations

Chemokine expression during hepatic ischemia/reperfusion-induced lung injury in the rat. The role of epithelial neutrophil activating protein.

1995 • 236 citations

The “injury response”: A concept linking nonspecific injury, acute rejection, and long-term transplant outcomes

1997 • 224 citations

Inhibition of leukocyte adherence by anti-CD18 monoclonal antibody attenuates reperfusion injury in the rabbit ear.

1990 • 205 citations

Endonuclease-induced DNA damage and cell death in oxidant injury to renal tubular epithelial cells.

1992 • 182 citations

Acute renal failure following cardiac surgery: incidence, outcomes and risk factors

1995 • 176 citations

Adenosine enhances IL-10 secretion by human monocytes.

1996 • 175 citations

Induction of Monocyte Chemoattractant Protein-1 in the Small Veins of the Ischemic and Reperfused Canine Myocardium

1997 • 173 citations

Slow release of soluble TNF receptors by monocytes in vitro.

1994 • 150 citations

Regulation of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor-1 by IFN-gamma, tumor necrosis factor-alpha, IgG aggregates, and cAMP in mouse mesangial cells.

1993 • 147 citations

Antibodies to ICAM-1 Protect Kidneys in Severe Ischemic Reperfusion Injury

1995 • 145 citations

The regulation of expression of major histocompatibility complex products.

1986 • 144 citations

Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends

1997 • 142 citations

Ischemia increases neutrophil retention and worsens acute renal failure: Role of oxygen metabolites and ICAM 1

1995 • 140 citations

Tumor necrosis factor-alpha induces cell type and tissue-specific expression of chemoattractant cytokines in vivo.

1993 • 139 citations

Analysis of cytokine mRNA levels in interleukin‐4‐transgenic mice by quantitative polymerase chain reaction

1992 • 139 citations

Interleukin-10 reduces the systemic inflammatory response in a murine model of intestinal ischemia/reperfusion

1997 • 132 citations

TNF α is localized to nasal mucosal mast cells and is released in acute allergic rhinitis

1995 • 128 citations

Nature of the renal injury following total renal ischemia in man.

1984 • 104 citations

Apoptosis After Intestinal Ischemia-Reperfusion Injury

1997 • 85 citations

Release of interleukin-12 in experimental Escherichia coli septic shock in baboons: relation to plasma levels of interleukin-10 and interferon- gamma

1996 • 84 citations

Interleukin-10 increases Bcl-2 expression and survival in primary human CD34+ hematopoietic progenitor cells

1996 • 83 citations

Dialysate to plasma solute concentration (D/P) versus peritoneal transport parameters in CAPD

1994 • 78 citations

IL-10 inhibits the synthesis of migration inhibitory factor and migration inhibitory factor-mediated macrophage activation.

1993 • 71 citations

Assessment of myeloperoxidase activity in renal tissue after ischaemia/reperfusion

1994 • 67 citations

Transplantation

1986 • 61 citations

Effect of antitumour necrosis factor treatment on circulating tumour necrosis factor levels and mortality after surgery in jaundiced mice

1993 • 52 citations

Exogenous Human Recombinant Interleukin-10 Attenuates Hindlimb Ischemia–Reperfusion Injury

1997 • 50 citations

Role of Tumour Necrosis Factor in the Enhanced Sensitivity of Mice to Endotoxin After Exposure to Lead

1989 • 44 citations

Human endothelial cells: effect of TNF-alpha on peripheral blood mononuclear cell adhesion.

1991 • 44 citations

Bactericidal/Permeability-Increasing Protein Release in Whole Blood Ex Vivo: Strong Induction by Lipopolysaccharide and Tumor Necrosis Factor-

1997 • 33 citations

Desferrioxamine regulates tumor necrosis factor release in mesangial cells

1991 • 30 citations

CALCIUM BLOCKADE REDUCES RENAL APOPTOSIS DURING ISCHEMIA REPERFUSION

1997 • 28 citations

Tumour necrosis factor mediates e-selectin production and leukocyte accumulation in myocardial ischaemia-reperfusion injury

1995 • 27 citations

Binding of antibodies raised against tumour necrosis factor alpha (TNF?) to blood vessels and macrophages in inflamed synovial tissue

1991 • 22 citations

Restricted T cell Vβ repertoire in renal allografts during acute and chronic rejection

1996 • 15 citations

Monoclonal antibody that distinguishes between a phosphorylated, beta 2-microglobulin-associated, and a free, nonphosphorylated, chain of MHC class I.

1993 • 15 citations

Induction of major histocompatibility complex markers and inflammatory cytokines after ischemic injury to the kidney: lessons from interferon-gamma gene knockout mice.

1995 • 14 citations

Many forms of renal injury induce a stereotyped response with increased expression of MHC, IFN-y, and adhesion molecules

1997 • 9 citations

Pretransplant sensitization with major histocompatibility complex class I+ class II− hepatocytes leads to accelerated skin graft rejection

1992 • 1 citations