Interleukin‐10 controls interferon‐γ and tumor necrosis factor production during experimental endotoxemia

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

IL-10 inhibits cytokine production by activated macrophages.

1991 • 2,919 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

1993 • 1,409 citations

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

1986 • 1,282 citations

Macrophage deactivation by interleukin 10.

1991 • 1,253 citations

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.

1991 • 976 citations

Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia.

1993 • 821 citations

Interleukin 10 protects mice from lethal endotoxemia.

1993 • 807 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

The role of IL-10 in crossregulation of TH1 and TH2 responses

1991 • 775 citations

Septic shock: pathogenesis

1991 • 743 citations

Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

1988 • 603 citations

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

1990 • 347 citations

Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha.

1992 • 300 citations

Interferon gamma inhibits interleukin 10 production by monocytes.

1993 • 294 citations

The role of IFN-gamma in the pathology of experimental endotoxemia.

1990 • 257 citations

Prophylactic and Therapeutic Effects of a Monoclonal Antibody to Tumor Necrosis Factor- in Experimental Gram-Negative Shock

1990 • 200 citations

The injection of deaggregated gamma globulins in adult mice induces antigen-specific unresponsiveness of T helper type 1 but not type 2 lymphocytes.

1992 • 139 citations

In vivo induction of interleukin 10 by anti-CD3 monoclonal antibody or bacterial lipopolysaccharide: differential modulation by cyclosporin A.

1993 • 124 citations

Interleukin‐10 inhibits the induction of monocyte procoagulant activity by bacterial lipopolysaccharide

1993 • 104 citations

Role of Interferon- in Experimental Gram-Negative Sepsis

1992 • 90 citations

Modified Immunological Status of Anti-IL-10 Treated Mice

1993 • 77 citations

Regulation of MHC expression in vivo. Bacterial lipopolysaccharide induces class I and II MHC products in mouse tissues by a T cell-independent, cyclosporine-sensitive mechanism.

1988 • 59 citations

Endogenous and exogenous glucocorticoids have different roles in modulating endotoxin lethality in D-galactosamine-sensitized mice

1993 • 30 citations

A role for interleukin 1 in the in vivo actions of tumor necrosis factor.

1989 • 18 citations