Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.

The incorporation of 3H-cytosine arabinoside and its effect on murine leukemic cells (L5178Y)

1968 • 296 citations

Efflux of methotrexate and its polyglutamate derivatives from hepatic cells in vitro.

1981 • 89 citations

Stoichiometric inhibition of mammalian dihydrofolate reductase by the γ-glutamyl metabolite of methotrexate, 4-amino-4-deoxy-N10-methylpteroylglutamyl-γ-glutamate

1975 • 81 citations

Human thymidylate synthetase—III

1979 • 62 citations

Accumulation of methotrexate diglutamate in human liver during methotrexate therapy

1977 • 57 citations

Synthesis of methotrexate polyglutamates in cultured human cells.

1978 • 54 citations

Characteristics of methotrexate polyglutamate formation in cultured hepatic cells

1982 • 47 citations

Synthesis of Methotrexate Polyglutamates by Bone Marrow Cells from Patients with Leukemia and Lymphoma

1980 • 41 citations

Extracellular recovery of methotrexate-polyglutamates following efflux from L1210 leukemia cells

1980 • 35 citations