Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

1999 • 2,128 citations

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1994 • 1,138 citations

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

1995 • 992 citations

Biology and clinical relevance of human natural killer cells

1990 • 930 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells.

1994 • 671 citations

IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39

1996 • 653 citations

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

1991 • 597 citations

Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells

1996 • 495 citations

The Interleukin-2 Receptor γ Chain: Its Role in the Multiple Cytokine Receptor Complexes and T Cell Development in XSCID

1996 • 411 citations

Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain

2000 • 322 citations

The hematopoietin receptor superfamily

1993 • 296 citations

CD40 ligand and its role in X-linked hyper-IgM syndrome

1993 • 257 citations

Flt3 Ligand Promotes the Generation of a Distinct CD34+Human Natural Killer Cell Progenitor That Responds to Interleukin-15

1998 • 222 citations

Crystal Structure of the Interleukin-4/Receptor α Chain Complex Reveals a Mosaic Binding Interface

1999 • 216 citations

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation.

1995 • 183 citations

Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.

1993 • 174 citations

Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain

1997 • 158 citations

Natural Killer Cells and Tumor Therapy

1998 • 143 citations

Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth.

1993 • 134 citations

Natural killer cell differentiation: insights from knockout and transgenic mouse models and in vitro systems

1998 • 131 citations

Animal Cell Technology

1997 • 85 citations

Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor.

1993 • 81 citations

Homodimerization of Interleukin-4 Receptor α Chain Can Induce Intracellular Signaling

1996 • 75 citations

Hematopoietic cytokines: Similarities and differences in the structures, with implications for receptor binding

1993 • 43 citations

Expression Augmenting Sequence Element (EASE) Isolated From Chinese Hamster Ovary Cells

1997 • 16 citations