Retinal expression, regulation, and functional bioactivity of prostacyclin-stimulating factor

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Diabetic Retinopathy

1974 • 5,744 citations

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

1994 • 3,652 citations

Oxygen-induced retinopathy in the mouse.

1994 • 1,564 citations

Untitled

1982 • 1,310 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

1995 • 1,280 citations

Increased Vascular Endothelial Growth Factor Levels in the Vitreous of Eyes With Proliferative Diabetic Retinopathy

1994 • 1,269 citations

Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization.

1995 • 1,021 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Fibroblast Growth Factor-2 (FGF-2) Induces Vascular Endothelial Growth Factor (VEGF) Expression in the Endothelial Cells of Forming Capillaries: An Autocrine Mechanism Contributing to Angiogenesis

1998 • 829 citations

Retinal Vascular Patterns

1961 • 785 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Vascular Endothelial Growth Factor–Induced Retinal Permeability Is Mediated by Protein Kinase C In Vivo and Suppressed by an Orally Effective β-Isoform–Selective Inhibitor

1997 • 665 citations

Vascular Endothelial Growth Factor/Vascular Permeability Factor Enhances Vascular Permeability Via Nitric Oxide and Prostacyclin

1998 • 506 citations

Regulation of Vascular Endothelial Growth Factor by Oxygen in a Model of Retinopathy of Prematurity

1996 • 498 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

1995 • 466 citations

Characterization of the Mechanism for the Chronic Activation of Diacylglycerol-Protein Kinase C Pathway in Diabetes and Hypergalactosemia

1994 • 444 citations

Vasodilator Therapy for Primary Pulmonary Hypertension in Children

1999 • 425 citations

Prostacyclin Synthesis Induced in Vascular Cells by Interleukin-1

1985 • 364 citations

Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation

1993 • 306 citations

Retinal blood flow changes in patients with insulin-dependent diabetes mellitus and no diabetic retinopathy.

1996 • 302 citations

Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A₂ in endothelial cells via p42/p44 mitogen‐activated protein kinase

1997 • 258 citations

Laser Doppler Velocimetry Study of Retinal Circulation in Diabetes Mellitus

1986 • 230 citations

Renal hypertrophy is associated with upregulation of TGF-beta 1 gene expression in diabetic BB rat and NOD mouse

1994 • 186 citations

Platelet-dependent stimulation of prostacyclin synthesis by platelet-derived growth factor

1980 • 185 citations

Capillary Shunts in the Pathogenesis of Diabetic Retinopathy

1963 • 160 citations

Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1.

1996 • 140 citations

Transcription Factors Sp1 and Sp3 Alter Vascular Endothelial Growth Factor Receptor Expression through a Novel Recognition Sequence

1998 • 136 citations

Cachectin/TNF as well as interleukin-1 induces prostacyclin synthesis in cultured vascular endothelial cells

1986 • 124 citations

Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-beta.

1998 • 116 citations

Retinal Blood Flow Alterations During Progression of Diabetic Retinopathy

1983 • 109 citations

Basic fibroblast growth factor induces expression of VEGF receptor KDR through a protein kinase C and p44/p42 mitogen-activated protein kinase-dependent pathway.

1999 • 102 citations

Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display.

1994 • 97 citations

Purification and molecular cloning of prostacyclin-stimulating factor from serum-free conditioned medium of human diploid fibroblast cells

1994 • 95 citations

Retinal blood flow changes in type I diabetes. A long-term follow-up study.

1996 • 93 citations

Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-?

1998 • 87 citations

Estimation of retinal blood flow by measurement of the mean circulation time

1971 • 74 citations

A Major Role for Prostacyclin in Nitric Oxide–Induced Ocular Vasorelaxation in the Piglet

1998 • 74 citations

Fluorescein dye-dilution technique and retinal circulation

1978 • 74 citations

Endothelin-1 action via endothelin receptors is a primary mechanism modulating retinal circulatory response to hyperoxia.

1996 • 74 citations

Vascular Pericytes Not Only Regulate Growth, but Also Preserve Prostacyclin-Producing Ability and Protect Against Lipid Peroxide-Induced Injury of Cocultured Endothelial Cells

1993 • 71 citations

Basic fibroblast growth factor mRNA, bFGF peptide and FGF receptor in epiretinal membranes of intraocular proliferative disorders (PVR and PDR)

1997 • 62 citations

Normalization of retinal blood flow in diabetic rats with primary intervention using insulin pumps.

1994 • 62 citations

Microvascular endothelial‐derived autacoids regulate pericyte contractility

1991 • 60 citations

Extravascular Lesions of Diabetic Retinopathy

1962 • 51 citations

Prostacyclin is the major prostaglandin synthesized by bovine retinal capillary pericytes in culture.

1988 • 44 citations

Retinal circulation times in quantitative fluorescein angiography

1990 • 40 citations

Human Retinal Vascular Cells Differ from Umbilical Cells in Synthetic Functions and Their Response to Glucose

1992 • 34 citations

Reversibility of retinal flow abnormalities is disease-duration dependent in diabetic rats.

1998 • 30 citations

Reversal of abnormal retinal hemodynamics in diabetic rats by acarbose, an α-glucosidase inhibitor

1995 • 30 citations

Epidermal Growth Factor Stimulates Prostacyclin Production by Cultured Human Vascular Endothelial Cells

1988 • 27 citations

Retinal Blood Flow Changes in Type I Diabetes

1996 • 26 citations

Pericytes of Newly Formed Vessels in Experimental Subretinal Neovascularization

1995 • 26 citations

Transforming growth factor α stimulates prostacyclin production by cultured human vascular endothelial cells more potently than epidermal growth factor

1989 • 24 citations

Expression of Prostacyclin-Stimulating Factor, a Novel Protein, in Tissues of Wistar Rats and in Cultured Cells

1994 • 16 citations

Increased mRNA expression of a novel prostacyclin-stimulating factor in human colon cancer

1998 • 15 citations

Immunohistochemical Study of Prostacyclin-Stimulating Factor (PSF) in the Diabetic and Atherosclerotic Human Coronary Artery

1997 • 13 citations

Prostacyclin-Stimulating Factor, Novel Protein, and Diabetic Angiopathy

1996 • 10 citations

Reduced Expression of a Novel Peptide, Prostacyclin-Stimulating Factor, in the Kidneys of Streptozotocin-Induced Diabetic Rats

1998 • 9 citations

Immunohistochemical Localization of a Novel Peptide, Prostacyclin-Stimulating Factor (PSF), in Human Tissues

1995 • 6 citations

Effect of high glucose concentrations on prostacyclin-stimulating factor mRNA expression in cultured aortic smooth muscle cells

1998 • 5 citations

Isolation and Characterization of the Human Chromosomal Gene for Prostacyclin-Stimulating Factor

1996 • 5 citations