Bone Marrow Stromal Damage after Chemo/Radiotherapy: Occurrence, Consequences and Possibilities of Treatment

Multilineage Potential of Adult Human Mesenchymal Stem Cells

1999 • 20,447 citations

Mesenchymal stem cells

1991 • 6,355 citations

Bone marrow transplant

1989 • 3,423 citations

Bone marrow transplant

1999 • 2,452 citations

In VitroChondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells

1998 • 2,347 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta

1999 • 1,841 citations

STROMAL CELLS RESPONSIBLE FOR TRANSFERRING THE MICROENVIRONMENT OF THE HEMOPOIETIC TISSUES

1974 • 1,360 citations

Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

2000 • 1,224 citations

Rapid Hematopoietic Recovery After Coinfusion of Autologous-Blood Stem Cells and Culture-Expanded Marrow Mesenchymal Stem Cells in Advanced Breast Cancer Patients Receiving High-Dose Chemotherapy

2000 • 1,115 citations

Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model

2000 • 1,024 citations

Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.

1995 • 922 citations

Marrow stromal stem cells

1988 • 835 citations

Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures

1992 • 829 citations

Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use.

1995 • 733 citations

Single-Colony Derived Strains of Human Marrow Stromal Fibroblasts Form Bone After Transplantation In Vivo

1997 • 722 citations

Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells

2000 • 709 citations

Allogeneic Bone‐Marrow Transplantation

1983 • 614 citations

BONE FORMATION IN VIVO: COMPARISON OF OSTEOGENESIS BY TRANSPLANTED MOUSE AND HUMAN MARROW STROMAL FIBROBLASTS

1997 • 488 citations

Fibroblast Growth Factor-2 Supports ex Vivo Expansion and Maintenance of Osteogenic Precursors from Human Bone Marrow*

1997 • 445 citations

A Quadripotential Mesenchymal Progenitor Cell Isolated from the Marrow of an Adult Mouse

1999 • 429 citations

Osteogenic Stem Cells and the Stromal System of Bone and Marrow

1989 • 394 citations

Repair of bone defects with marrow cells and porous ceramic: Experiments in rats

1989 • 371 citations

Bone progenitor cell deficits and the age-associated decline in bone repair capacity

1995 • 348 citations

The Osteogenic Potential of Culture-Expanded Rat Marrow Mesenchymal Cells Assayed In Vivo in Calcium Phosphate Ceramic Blocks

1991 • 346 citations

Stromal cell associated haemopoiesis

1982 • 325 citations

Host origin of marrow stromal cells following allogeneic bone marrow transplantation

1987 • 323 citations

The ultrastructure of the hemopoietic environment of the marrow: a review.

1981 • 308 citations

The hematopoietic microenvironment of the bone marrow: An ultrastructural study of the stroma in rats

1976 • 307 citations

Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients

1999 • 281 citations

Osteogenic stem cells in the bone marrow

1990 • 239 citations

Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation

2000 • 235 citations

Requirement of donor-derived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation. Complete prevention of recurrence of autoimmune diseases in MRL/MP-Ipr/Ipr mice by transplantation of bone marrow plus bones (stromal cells) from the same donor.

1994 • 197 citations

Bone marrow regeneration after local injury: a review.

1975 • 177 citations

Mechanisms of Bone Loss Following Allogeneic and Autologous Hemopoietic Stem Cell Transplantation

1999 • 168 citations

Human bone tissue formation in diffusion chamber culture in vivo by bone-derived cells and marrow stromal fibroblastic cells

1995 • 166 citations

Hemopoietic stromal microenvironment

1983 • 165 citations

Engraftment of a clonal bone marrow stromal cell line in vivo stimulates hematopoietic recovery from total body irradiation.

1987 • 159 citations

Fibroblast Growth Factor-2 Supports ex Vivo Expansion and Maintenance of Osteogenic Precursors from Human Bone Marrow

1997 • 155 citations

Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture.

1989 • 149 citations

Osteoblasts promote engraftment of allogeneic hematopoietic stem cells.

1998 • 140 citations

Long-term bone marrow damage in experimental systems and in patients after radiation or chemotherapy.

1985 • 139 citations

A prospective study of bone loss and turnover after allogeneic bone marrow transplantation: effect of calcium supplementation with or without calcitonin

1999 • 115 citations

RECONSTITUTION OF HAEMOPOIETIC SYSTEM WITH AUTOLOGOUS MARROW TAKEN DURING RELAPSE OF ACUTE MYELOBLASTIC LEUKAEMIA AND GROWN IN LONG-TERM CULTURE

1986 • 107 citations

Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe in 1998

1998 • 107 citations

Mechanisms of osteoporosis after hematopoietic cell transplantation

2000 • 106 citations

Bone Loss in Long-Term Survivors after Transplantation of Hematopoietic Stem Cells: A Prospective Study

2000 • 97 citations

Long-term marrow culture: an overview of techniques and experience.

1984 • 92 citations

Effect of chemotherapy for acute myelogenous leukemia on hematopoietic and fibroblast marrow progenitors

1997 • 83 citations

Hemopoietic reconstitution after bone marrow transplantation.

1986 • 82 citations

Bone mineral density in patients undergoing bone marrow transplantation for myeloid malignancies

1998 • 81 citations

Diseases of Bone and the Stromal Cell Lineage

1999 • 80 citations

Bone mass after allogeneic BMT for childhood leukaemia or lymphoma

2000 • 76 citations

Marrow biology and stem cells.

1990 • 71 citations

Effects of cyclophosphamide and of busulfan on spleen colony-forming units and on hematopoietic stroma.

1977 • 65 citations

Reduction of Bone Mass in Women after Bone Marrow Transplantation

1997 • 64 citations

CGA-7 and HHF, two monoclonal antibodies that recognize muscle actin and react with adherent cells in human long-term bone marrow cultures

1985 • 63 citations

Prolonged impairment of hematopoiesis after high-dose therapy followed by autologous bone marrow transplantation

1995 • 61 citations

Reduced bone mineral density in men and women with allogeneic bone marrow transplantation.

1990 • 59 citations

Osteoporosis after blood and marrow transplantation: Clinical aspects

2000 • 57 citations

Clonogenic hemopoietic precursors in bone marrow transplantation

1987 • 56 citations

Toxic effects on the hematopoietic microenvironment.

1991 • 56 citations

The cellular basis of long-term marrow injury after irradiation

1985 • 55 citations

Haemopoiesis of transplanted patients with autologous marrows assessed by long‐term marrow culture

1994 • 54 citations

REDUCED BONE MINERAL DENSITY IN MEN AND WOMEN WITH ALLOGENEIC BONE MARROW TRANSPLANTATION

1990 • 53 citations

Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders. Current practice in Europe in 1996 and proposals for an operational classification. Accreditation Sub-Committee of the European Group for Blood and Marrow Transplantation (EBMT).

1996 • 51 citations

Characterization of the in vitro stromal microenvironment of human bone marrow

1986 • 50 citations

A New Strategy for Treatment of Autoimmune Diseases in Chimeric Resistant MRL/lpr Mice

1998 • 50 citations

Bone mineral density after allogeneic bone marrow transplantation

1999 • 42 citations

Deficient reconstitution of early progenitors after allogeneic bone marrow transplantation

1997 • 42 citations

Haemopoietic reconstitution after allogeneic bone marrow transplantation in man: recovery of haemopoietic progenitors (CFU‐Mix, BFU‐E and CFU‐GM)

1987 • 37 citations

Alterations in both the hematopoietic microenvironment and the progenitor cell population follow the recovery from myeloablative therapy and bone marrow transplantation.

1995 • 37 citations

Haematopoietic damage persists 1 year after autologous peripheral blood stem cell transplantation

1999 • 35 citations

Residual marrow damage following therapy with cyclophosphamide.

1980 • 34 citations

Haematopoietic abnormalities after autologous stem cell transplantation in lymphoma patients

1998 • 33 citations

Changes in the Functional Capacity of Marrow Stromal Cells after Autologous Bone Marrow Transplantation

1998 • 32 citations

Donor stromal cells from human blood engraft in NOD/SCID mice

2000 • 31 citations

Host origin of bone marrow fibroblasts following allogeneic bone marrow transplantation for chronic myeloid leukemia.

1992 • 31 citations

The Mechanisms Involved in the Impairment of Hematopoiesis after Autologous Bone Marrow Transplantation

1997 • 27 citations

Radiation damage to femoral hemopoietic stroma measured by implant regeneration and quantitation of fibroblastic progenitors.

1983 • 22 citations

The long-term effects of MVPP chemotherapy for Hodgkin's disease on bone marrow function

1990 • 19 citations

An analysis of haemopoietic and microenvironmental populations of mouse bone marrow after treatment with busulphan.

1986 • 17 citations

A cellular analysis of long-term haematopoietic damage in mice after repeated treatment with cyclophosphamide

1986 • 15 citations

Hematopoietic damage prior to PBSCT and its influence on hematopoietic recovery.

1999 • 14 citations

Powers of differentiation of clonal strains of bone marrow fibroblasts

1986 • 11 citations

Incomplete stroma formation after allogeneic marrow or autologous blood stem cell transplantation.

1992 • 11 citations

Quality and functional capacity of the bone marrow microenvironment of autologous blood stem cell transplantation (ABSCT) recipients.

1994 • 9 citations

[Differentiation potentials of clonal strains of bone marrow fibroblasts].

1986 • 5 citations