Donor stromal cells from human blood engraft in NOD/SCID mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Multilineage Potential of Adult Human Mesenchymal Stem Cells

1999 • 20,447 citations

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

1997 • 8,673 citations

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1997 • 6,760 citations

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1994 • 4,563 citations

Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro

1997 • 2,492 citations

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

1999 • 2,425 citations

Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors

2000 • 2,286 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Evidence for Circulating Bone Marrow-Derived Endothelial Cells

1998 • 1,666 citations

Origins of circulating endothelial cells and endothelial outgrowth from blood

2000 • 1,529 citations

Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation

1997 • 1,471 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

The most promising surrogate endpoint biomarkers for screening candidate chemopreventive compounds for prostatic adenocarcinoma in short-term phase II clinical trials.

1994 • 850 citations

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy

1996 • 795 citations

The Biology and Clinical Uses of Blood Stem Cells

1997 • 729 citations

Mesenchymal stem cells in bone development, bone repair, and skeletal regenaration therapy

1994 • 702 citations

Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies

1992 • 650 citations

Long-term culture of human bone marrow cells.

1980 • 624 citations

Cytokine Stimulation of Multilineage Hematopoiesis from Immature Human Cells Engrafted in SCID Mice

1992 • 555 citations

KDR Receptor: A Key Marker Defining Hematopoietic Stem Cells

1999 • 491 citations

Primitive Human Hematopoietic Cells Are Enriched in Cord Blood Compared With Adult Bone Marrow or Mobilized Peripheral Blood as Measured by the Quantitative In Vivo SCID-Repopulating Cell Assay

1997 • 488 citations

BONE FORMATION IN VIVO: COMPARISON OF OSTEOGENESIS BY TRANSPLANTED MOUSE AND HUMAN MARROW STROMAL FIBROBLASTS

1997 • 488 citations

Host origin of marrow stromal cells following allogeneic bone marrow transplantation

1987 • 323 citations

CD34 expression by stromal precursors in normal human adult bone marrow

1991 • 289 citations

Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man

1982 • 255 citations

Kinetic Evidence of the Regeneration of Multilineage Hematopoiesis From Primitive Cells in Normal Human Bone Marrow Transplanted Into Immunodeficient Mice

1997 • 247 citations

Structure, Organization, and Sequence of Alpha Satellite DNA from Human Chromosome 17: Evidence for Evolution by Unequal Crossing-Over and an Ancestral Pentamer Repeat Shared With the Human X Chromosome

1986 • 238 citations

Phenotype and function of human hematopoietic cells engrafting immune- deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells

1996 • 204 citations

LacZ and Interleukin-3 ExpressionIn Vivoafter Retroviral Transduction of Marrow-Derived Human Osteogenic Mesenchymal Progenitors

1997 • 161 citations

Detection of stromal cells in peripheral blood progenitor cell collections from breast cancer patients

1997 • 159 citations

Osteogenic differentiation of purified, culture‐expanded human mesenchymal stem cells in vitro

1997 • 153 citations

Structure, organization, and sequence of alpha satellite DNA from human chromosome 17: evidence for evolution by unequal crossing-over and an ancestral pentamer repeat shared with the human X chromosome.

1986 • 150 citations

Origin of Human Bone Marrow Fibroblasts

1980 • 124 citations

Sustained proliferation, multi‐lineage differentiation and maintenance of primitive human haemopoietic cells in NOD/SCID mice transplanted with human cord blood

1997 • 117 citations

PCR amplification of chromosome-specific alpha satellite DNA: Definition of centromeric STS markers and polymorphic analysis

1991 • 108 citations

Engraftment of immune-deficient mice with primitive hematopoietic cells from β-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols

1995 • 91 citations

Effect of chemotherapy for acute myelogenous leukemia on hematopoietic and fibroblast marrow progenitors

1997 • 83 citations

An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells

1998 • 77 citations

Human Cord Blood Progenitors Sustain Thymic T-Cell Development and a Novel Form of Angiogenesis

1999 • 64 citations

Expression of Biologically Active Isoforms of the Tumor Angiogenesis Factor VEGF inEscherichia coli

1996 • 58 citations

Cyclophosphamide-induced alterations of bone marrow endothelium: implications in homing of marrow cells after transplantation.

1991 • 54 citations

Possible mechanisms accounting for the growth factor independence of hematopoietic progenitors from umbilical cord blood

1994 • 53 citations

Fibroblast markers in labial salivary gland biopsies in progressive systemic sclerosis.

1990 • 44 citations

Maintenance and proliferation control of primitive hemopoietic progenitors in long-term cultures of human marrow cells.

1988 • 43 citations

The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis

1995 • 39 citations

Umbilical cord blood biology and transplantation

1995 • 31 citations

Ultrastructural changes of stromal cells of bone marrow and liver after cyclophosphamide treatment in mice

1997 • 24 citations

Detection of human cells in human/sheep chimeric lambs with in vitro human stroma-forming potential.

1996 • 22 citations

Fibroblasts retrovirally transfected with the human IL-3 gene initiate and sustain multilineage human hematopoiesis in SCID mice: comparison of CD34-enriched vs CD34-enriched and in vitro expanded grafts.

1996 • 15 citations