Aspirin-Triggered Lipoxin A4 and B4 Analogs Block Extracellular Signal-Regulated Kinase-Dependent TNF-α Secretion from Human T Cells

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 • 3,026 citations

Lipid mediator class switching during acute inflammation: signals in resolution

2001 • 1,355 citations

Differentiation Stage-Specific Inhibition of the Raf-MEK-ERK Pathway by Akt

1999 • 762 citations

Development of anti-TNF therapy for rheumatoid arthritis

2002 • 673 citations

Cytokines and autoimmunity

2002 • 663 citations

Lysophospholipids--Receptor Revelations

2001 • 539 citations

Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor.

1994 • 431 citations

Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors

1997 • 427 citations

Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis

2002 • 393 citations

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R

2002 • 356 citations

Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level

2001 • 334 citations

Critical Roles for Interleukin 1 and Tumor Necrosis Factor α in Antibody-induced Arthritis

2002 • 327 citations

Design of Lipoxin A4 Stable Analogs That Block Transmigration and Adhesion of Human Neutrophils

1995 • 326 citations

Lipoxin A4 Stable Analogs Are Potent Mimetics That Stimulate Human Monocytes and THP-1 Cells via a G-protein-linked Lipoxin A4 Receptor

1997 • 266 citations

Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation

2000 • 262 citations

Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity

2001 • 260 citations

Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis

2002 • 257 citations

Lipoxin A4 Inhibits IL-1β-Induced IL-6, IL-8, and Matrix Metalloproteinase-3 Production in Human Synovial Fibroblasts and Enhances Synthesis of Tissue Inhibitors of Metalloproteinases

2000 • 216 citations

Identification of a Human Enterocyte Lipoxin A4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon γ and Inhibits Tumor Necrosis Factor α–induced IL-8 Release

1998 • 209 citations

Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitmentin vivo

1999 • 209 citations

Lysophospholipids and their G protein-coupled receptors in inflammation and immunity

2002 • 179 citations

Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids.

1996 • 168 citations

The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis

2000 • 150 citations

Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways

2001 • 149 citations

Lipoxins: revelations on resolution

2001 • 145 citations

15-Epi-16-(Para-Fluorophenoxy)-Lipoxin A4-Methyl Ester, a Synthetic Analogue of 15-epi-Lipoxin A4, Is Protective in Experimental Ischemic Acute Renal Failure

2002 • 142 citations

Lipoxins Are Potential Endogenous Antiinflammatory Mediators in Asthma

2002 • 139 citations

Human T-lymphocyte subset specificity of the regulatory effects of leukotriene B4.

1984 • 131 citations

Lipoxin A4 Antagonizes the Mitogenic Effects of Leukotriene D4 in Human Renal Mesangial Cells

2000 • 119 citations

α-Tocopherol transfer protein stimulates the secretion of α-tocopherol from a cultured liver cell line through a brefeldin A-insensitive pathway

1997 • 117 citations

Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

2001 • 110 citations

Lipoxin B₄regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B₄analogs with increased biologic activity

1998 • 89 citations

5(S),15(S)-dihydroxyeicosatetraenoic acid and lipoxin generation in human polymorphonuclear cells: dual specificity of 5-lipoxygenase towards endogenous and exogenous precursors.

1996 • 82 citations

Activation of human monocytes and the acute monocytic leukemia cell line (THP-1) by lipoxins involves unique signaling pathways for lipoxin A4 versus lipoxin B4: evidence for differential Ca2+ mobilization.

1996 • 80 citations

Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines.

1994 • 78 citations

A Specific Inhibitor of the p38 Mitogen Activated Protein Kinase Affects Differentially the Production of Various Cytokines by Activated Human T Cells: Dependence on CD28 Signaling and Preferential Inhibition of IL-10 Production

1999 • 74 citations

Pulmonary miliary tuberculosis in a patient with anti-TNF-alpha treatment

2002 • 73 citations

Aspirin‐triggered lipoxin A ₄ and lipoxin A ₄ up‐regulate transcriptional corepressor NAB1 in human neutrophils

2001 • 64 citations

Increased expression of tumor necrosis factor-α messenger RNA in the intestinal mucosa of inflammatory bowel disease, particularly in patients with disease in the inactive phase

2002 • 59 citations

Decreased IL-12 production and Th1 cell development by acetyl salicylic acid-mediated inhibition of NF-κB

1998 • 54 citations

The Role of TNF/TNFR in Organ-Specific and Systemic Autoimmunity: Implications for the Design of Optimized 'Anti-TNF� Therapies

2001 • 41 citations

Cell-Cell Interactions in the Release of Inflammatory Mediators

1991 • 26 citations

IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components

2002 • 26 citations

A Novel Long Chain Polyunsaturated Fatty Acid, β-Oxa 21:3n-3, Inhibits T Lymphocyte Proliferation, Cytokine Production, Delayed-Type Hypersensitivity, and Carrageenan-Induced Paw Reaction and Selectively Targets Intracellular Signals

2001 • 22 citations

Leukotriene B4 modulates in vivo expression of delayed-type hypersensitivity by a receptor-mediated mechanism: regulation by lipoxin A4.

1996 • 18 citations

LTB4 and PAF in the Cytokine Network

1991 • 13 citations

Enhanced lymphokine production and lymphokine receptor expression in multiple antibody-stimulated human CD4+ peripheral blood lymphocytes.

1992 • 11 citations