Chloral hydrate disrupts mitosis by increasing intracellular free calcium

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Changes of free calcium levels with stages of the cell division cycle

1985 • 591 citations

Calcium Rises Abruptly and Briefly Throughout the Cell at the Onset of Anaphase

1986 • 541 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

Control of microtubule assembly-disassembly by calcium-dependent regulator protein.

1978 • 493 citations

Tubulin dynamics in cultured mammalian cells.

1984 • 489 citations

Chapter 7 Immunofluorescence and Immunocytochemical Procedures with Affinity Purified Antibodies: Tubulin-Containing Structures

1982 • 382 citations

Cellular and Subcellular Heterogeneity of [Ca ²⁺ ] _i in Single Heart Cells Revealed by Fura-2

1987 • 345 citations

Localization of calcium channels in Paramecium caudatum.

1977 • 252 citations

Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): Studies in smooth muscles

1974 • 217 citations

Membrane Transport of Calcium

1983 • 197 citations

Studies on the in vivo sensitivity of spindle microtubules to calcium ions and evidence for a vesicular calcium-sequestering system.

1981 • 193 citations

Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules.

1983 • 181 citations

The Calcium Signal

1985 • 176 citations

THE ANAPHASE MOVEMENT OF CHROMOSOMES IN THE SPERMATOCYTES OF THE GRASSHOPPER

1949 • 174 citations

The role of calcium ions during mitosis

1983 • 166 citations

Calcium-labile mitotic spindles isolated from sea urchin eggs (Lytechinus variegatus).

1980 • 158 citations

Selective inhibition of the transmembrane Ca conductivity of mammalian myocardial fibres by Ni, Co and Mn ions

1973 • 157 citations

Microtubule Dynamics during the Cell Cycle: The Effects of Taxol and Nocodazole on the Microtubule System of Pt K2 Cells at Different Stages of the Mitotic Cycle

1986 • 143 citations

Membranes in the Mitotic Apparatus: Their Structure and Function

1984 • 119 citations

THE EFFECTS OF CARBON MONOXIDE INHIBITION ON ATP LEVEL AND THE RATE OF MITOSIS IN THE SEA URCHIN EGG

1963 • 114 citations

Calcium restriction prolongs metaphase in dividing Tradescantia stamen hair cells.

1985 • 107 citations

Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells.

1986 • 103 citations

Structure and control of assembly of cytoplasmic microtubules in normal and transformed cells

1976 • 88 citations

Tubulin sulfhydryl groups and polymerization in vitro

1977 • 85 citations

Regulation of Ca²⁺-Mg²⁺-ATPase Activity in Hepatocyte Plasma Membranes by Vasopressin and Phenylephrine*

1983 • 84 citations

Characterization and immunocytochemical distribution of calmodulin in higher plant endosperm cells: localization in the mitotic apparatus.

1985 • 82 citations

Nondisjunction induced in mouse spermatogenesis by chloral hydrate, a metabolite of trichloroethylene

1984 • 55 citations

Increases in internal Ca2+ and decreases in internal H+ are induced by general anesthetics in squid axons

1986 • 34 citations

Effect of microinjectecd calcium‐calmodulin on mitosis in PtK2 cells

1987 • 34 citations

Tests which distinguish induced crossing-over and aneuploidy from secondary segregation in Aspergillus treated with chloral hydrate or γ-rays

1986 • 31 citations

Metabolic inhibitors and mitosis: I. Effects of dinitrophenol/deoxyglucose and nocodazole on the live spindle

1986 • 29 citations

The Effect of Chloral Hydrate upon Mitosis in Aspergillus nidulans

1975 • 21 citations

Chromosome movements in chloral hydrate treated endosperm cells in vitro

1967 • 21 citations

Microtubules during germinal vesicle breakdown (GVBD) of Xenopus oocytes : effect of Ca²⁺ ionophore A-23187 and taxol

1985 • 20 citations

Chapter 19 Simple Methods and Devices for Handling Echinoderm Eggs

1986 • 9 citations

Calcium, spindle microtubule dynamics and chromosome movement

1982 • 8 citations

Chloral hydrate inhibition in vitro of ATPase in membrane of rat erythrocytes and in microsomes of dog kidney external medulla

1983 • 3 citations