Multigene Tracking of Hepatitis C Virus Quasispecies after Liver Transplantation: Correlation of Genetic Diversification in the Envelope Region with Asymptomatic or Mild Disease Patterns

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Genetic organization and diversity of the hepatitis C virus.

1991 • 1,717 citations

Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region

1993 • 1,401 citations

Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution

1992 • 938 citations

Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease

1991 • 854 citations

Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes

1993 • 788 citations

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

1992 • 712 citations

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

1995 • 702 citations

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins

1991 • 611 citations

Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.

1991 • 609 citations

Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

1996 • 607 citations

Recurrent and acquired hepatitis C viral infection in liver transplant recipients

1992 • 511 citations

Molecular Characterization of Pestiviruses

1996 • 506 citations

Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization.

1994 • 496 citations

Survey of major genotypes and subtypes of hepatitis C virus using RFLP of sequences amplified from the 5' non-coding region

1995 • 419 citations

Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus

1993 • 374 citations

Hypervariable regions in the putative glycoprotein of hepatitis C virus

1991 • 353 citations

There are two major types of hepatitis C virus in Japan

1990 • 335 citations

Sequence analysis of the core gene of 14 hepatitis C virus genotypes.

1994 • 315 citations

Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection

1997 • 306 citations

The course of hepatitis C virus infection after liver transplantation

1994 • 296 citations

Quantitation of hepatitis C virus RNA in liver transplant recipients

1994 • 291 citations

Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay.

1992 • 275 citations

Assessment of Hepatitis C Virus RNA Levels by Quantitative Competitive RNA Polymerase Chain Reaction: High-Titer Viremia Correlates with Advanced Stage of Disease

1994 • 219 citations

Multiple Enzymatic Activities Associated with Recombinant NS3 Protein of Hepatitis C Virus

1998 • 194 citations

Persistent hepatitis C virus infection after liver transplantation: Clinical and virological features

1995 • 188 citations

Severity of liver disease in liver transplantation recipients with hepatitis C virus infection: Relationship to genotype and level of viremia

1996 • 180 citations

Tracking hepatitis C virus quasispecies major and minor variants in symptomatic and asymptomatic liver transplant recipients

1996 • 148 citations

Assessment of Hepatitis C Viremia Using Molecular Amplification Technologies: Correlations and Clinical Implications

1995 • 147 citations

Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection

1993 • 138 citations

Evolution of Hepatitis C Virus Quasispecies in Hypervariable Region 1 and the Putative Interferon Sensitivity-Determining Region during Interferon Therapy and Natural Infection

1998 • 135 citations

Mutations in the NS5A gene of hepatitis C virus in North American patients infected with HCV genotype 1a or 1b

1997 • 119 citations

Histological and clinical outcome after liver transplantation for hepatitis C

1997 • 99 citations

Dynamic behavior of hepatitis C virus quasispecies in patients undergoing orthotopic liver transplantation

1994 • 90 citations

Assessment of Hepatitis C Virus Quasispecies Heterogeneity by Gel Shift Analysis: Correlation with Response to Interferon Therapy

1997 • 79 citations

Characterization of simple and complex hepatitis C virus quasispecies by heteroduplex gel shift analysis: correlation with nucleotide sequencing

1995 • 68 citations

Detection of hepatitis C virus RNA: comparison of one-stage polymerase chain reaction (PCR) with nested-set PCR

1993 • 63 citations

How Escherichia coli can bias the results of molecular cloning: Preferential selection of defective genomes of hepatitis C virus during the cloning procedure

1997 • 63 citations

Comparison of several PCR procedures for detection of serum HCV-RNA using different regions of the HCV genome

1992 • 55 citations

Molecular evolutionary virology: Its application to hepatitis C virus

1994 • 45 citations

Hepatitis C virus recurrence after liver transplantation: relationship to anti-HCV core IgM, genotype, and level of viremia.

1997 • 29 citations

Antibody response to hepatitis C virus infection after liver transplantation.

1994 • 17 citations

Detection of Hepatitis C After Liver Transplantation:Four Serologic Tests Compared

1995 • 15 citations