Consecutive screening and enrollment in clinical trials: The way to representative patient samples?

Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1992 • 5,885 citations

Effects of Enalapril on Mortality in Severe Congestive Heart Failure

1987 • 4,763 citations

The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure

1996 • 4,580 citations

Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)

1988 • 3,818 citations

Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo

1991 • 3,106 citations

The Effect of Digoxin on Mortality and Morbidity in Patients with Heart Failure

1997 • 2,867 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure

1993 • 1,775 citations

A Clinical Trial of the Angiotensin-Converting–Enzyme Inhibitor Trandolapril in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1995 • 1,734 citations

Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)

1997 • 1,680 citations

Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction

1996 • 1,352 citations

Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT

1997 • 1,108 citations

Effect of the Antiarrhythmic Agent Moricizine on Survival after Myocardial Infarction

1992 • 969 citations

Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT

1997 • 946 citations

Recent Trends in Acute Coronary Heart Disease — Mortality, Morbidity, Medical Care, and Risk Factors

1996 • 705 citations

Randomised study of effect of ibopamine on survival in patients with advanced severe heart failure

1997 • 350 citations

Rational Diagnosis and Treatment

1986 • 251 citations

Clinical Guideline: Part II: Risk Stratification after Myocardial Infarction

1997 • 193 citations

Short and long term prognosis of acute myocardial infarction since introduction of thrombolysis.

1993 • 179 citations

Dofetilide in patients with left ventricular dysfunction and either heart failure or acute myocardial infarction: Rationale, design, and patient characteristics of the DIAMOND studies

1997 • 107 citations

Characteristics and prognosis of patients with acute myocardial infarction in relation to occurrence of congestive heart failure

1994 • 92 citations

Clinical Characteristics and Mortality of Patients Screened for Entry Into the Trandolapril Cardiac Evaluation (TRACE) Study

1995 • 79 citations

Rational Diagnosis and Treatment

1976 • 39 citations

The SWORD of Damocles

1996 • 32 citations