Highly Attenuated Vaccine Strains of Simian Immunodeficiency Virus Protect against Vaginal Challenge: Inverse Relationship of Degree of Protection with Level of Attenuation

Gastrointestinal Tract as a Major Site of CD4 ⁺ T Cell Depletion and Viral Replication in SIV Infection

1998 • 1,408 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

The common mucosal immune system and current strategies for induction of immune responses in external secretions

1987 • 810 citations

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques.

1996 • 705 citations

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus

1996 • 325 citations

Identification of Highly Attenuated Mutants of Simian Immunodeficiency Virus

1998 • 226 citations

Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells

1995 • 219 citations

Plasma SIV RNA Viral Load Determination by Real-Time Quantification of Product Generation in Reverse Transcriptase-Polymerase Chain Reaction

1998 • 205 citations

Macaques Infected with Live Attenuated SIVmac Are Protected against Superinfection via the Rectal Mucosa

1997 • 169 citations

Long-term Persistent Infection of Macaque Monkeys with the Simian Immunodeficiency Virus

1987 • 162 citations

Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus

1997 • 157 citations

Evolution of envelope-specific antibody responses in monkeys experimentally infected or immunized with simian immunodeficiency virus and its association with the development of protective immunity

1997 • 154 citations

Temporal Analyses of Virus Replication, Immune Responses, and Efficacy in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine

1998 • 149 citations

Recombinant Vaccine-Induced Protection against the Highly Pathogenic Simian Immunodeficiency Virus SIV_mac251: Dependence on Route of Challenge Exposure

1998 • 146 citations

Smallpox and Vaccinia

2017 • 145 citations

A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge

1994 • 142 citations

Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus

1997 • 142 citations

Rhesus macaques previously infected with simian/human immunodeficiency virus are protected from vaginal challenge with pathogenic SIVmac239

1997 • 135 citations

Protective immunity induced by live attenuated simian immunodeficiency virus

1998 • 128 citations

Mucosal immunity, HIV transmission, and AIDS.

1993 • 127 citations

Targeted lymph-node immunization with whole inactivated simian immunodeficiency virus (SIV) or envelope and core subunit antigen vaccines does not reliably protect rhesus macaques from vaginal challenge with SIVmac251

1998 • 126 citations

Cell Fusion Activity of the Simian Immunodeficiency Virus Envelope Protein Is Modulated by the Intracytoplasmic Domain

1993 • 118 citations

Update: The Numbers Game for Virus-Specific CD8 ⁺ T Cells

1998 • 91 citations

Titration and Characterization of Two Rhesus-Derived SIV_macChallenge Stocks

1994 • 84 citations

Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene

1994 • 80 citations

High-Titer Immune Responses Elicited by Recombinant Vaccinia Virus Priming and Particle Boosting Are Ineffective in Preventing Virulent SIV Infection

1994 • 61 citations

Protection of human immunodeficiency virus type 2-exposed seronegative macaques from mucosal simian immunodeficiency virus transmission

1997 • 58 citations

Protection against Mucosal SIV_smChallenge in Macaques Infected with a Chimeric SIV that Expresses HIV Type 1 Envelope

1996 • 57 citations

Efficacy of live‐attenuated and whole‐inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV

1992 • 55 citations

Neutralizing Antibodies in Sera from Macaques Immunized with Attenuated Simian Immunodeficiency Virus

1998 • 48 citations

Anti-viral immunity: Spotting virus-specific T cells

1998 • 17 citations

Properties of virus-like particles produced by SIV-chronically infected human cell clones.

1995 • 15 citations

Candidate vaccines protect macaques against primate immunodeficiency viruses.

1998 • 12 citations