Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents.

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

1963 • 801 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

1980 • 371 citations

A rapid single step staining technique for DNA analysis by flow microfluorimetry.

1980 • 294 citations

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines

1981 • 183 citations

Repair of DNA damaged by alkylating carcinogens is defective in xeroderma pigmentosum-derived fibroblasts

1977 • 109 citations

Mechanism of melphalan resistance developed in vitro in human melanoma cells.

1981 • 79 citations

The molecular basis of drug-induced G2 arrest in mammalian cells

1980 • 75 citations

CELLULAR REACTIVATION OF ULTRAVIOLET‐IRRADIATED HUMAN ADENOVIRUS 2 IN NORMAL AND XERODERMA PIGMENTOSUM FIBROBLASTS

1974 • 74 citations

Decreased DNA repair synthesis and defective colony-forming ability of ataxia telangiectasia fibroblast cell strains treated with N-methyl-N'-nitro-N-nitrosoguanidine.

1980 • 69 citations

Time course of O6-methylguanine removal from DNA of N-methyl-N-nitrosourea-treatedhuman fibroblasts

1981 • 69 citations

HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses

1979 • 65 citations

Enzymic excision of 3-methyladenine and 7-methylguanine by a rat liver nuclear fraction

1981 • 58 citations

Mechanism of action of 5-(3,3-dimethyl-1-triazeno)imidazole-4-caboxamide in mammalian cells in culture

1972 • 47 citations

Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents.

1981 • 43 citations

Effects of certain nitrogen mustards upon the progression of cultured H.Ep. no. 2 cells through the cell cycle.

1970 • 33 citations

Crosslinking of methylated DNA by moderate heating at neutral pH

1972 • 31 citations

Organ-specific effects of DNA methylation by alkylating agents in the inbred Swiss mouse

1975 • 29 citations

Effects of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (NSC-407347), An alkylating agent derived from 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388)

1975 • 25 citations

Properties of human melanoma cells resistant to 5-(3',3'-dimethyl-1-triazeno)imidazole-4-carboxamide and other methylating agents.

1982 • 24 citations

Cycle-dependent removal of certain methylated bases from DNA of 10T1/2 cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.

1981 • 21 citations