Some questions concerning a small, more electronegative LDL circulating in human plasma

Beyond Cholesterol

1989 • 6,533 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Protein damage and degradation by oxygen radicals. I. general aspects.

1987 • 1,618 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA

1973 • 1,457 citations

Lipid peroxides and human diseases

1987 • 1,358 citations

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

1987 • 1,152 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Receptor-Mediated Control of Cholesterol Metabolism

1976 • 957 citations

Minimally modified low density lipoprotein stimulates monocyte endothelial interactions.

1990 • 930 citations

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

1980 • 851 citations

Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene

1991 • 788 citations

Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins

1990 • 785 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products.

1987 • 625 citations

Role of oxidatively modified LDL in atherosclerosis

1990 • 614 citations

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

1984 • 547 citations

Lipoprotein oxidation and lipoprotein-induced cytotoxicity.

1983 • 545 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

1987 • 473 citations

Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor.

1986 • 417 citations

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells.

1983 • 396 citations

Presence of a modified low density lipoprotein in humans.

1988 • 373 citations

Fatty streak initiation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits.

1987 • 337 citations

Altered Metabolism (In Vivo and In Vitro) of Plasma Lipoproteins after Selective Chemical Modification of Lysine Residues of the Apoproteins

1979 • 313 citations

Oxidized low density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery.

1990 • 312 citations

Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia.

1983 • 282 citations

Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

1978 • 276 citations

Antioxidant treatment of diabetic rats inhibits lipoprotein oxidation and cytotoxicity.

1989 • 265 citations

Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma

1988 • 255 citations

Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.

1989 • 250 citations

Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low density lipoprotein.

1985 • 249 citations

Modification of human low-density lipoprotein by the lipid peroxidation product 4-hydroxynonenal

1986 • 241 citations

Plasma Vitamins E and A Inversely Correlated to Mortality from Ischemic Heart Disease in Cross‐Cultural Epidemiology

1989 • 240 citations

Injury to human endothelial cells in culture induced by low density lipoproteins

1979 • 231 citations

Role of lysines in mediating interaction of modified low density lipoproteins with the scavenger receptor of human monocyte macrophages.

1984 • 213 citations

Effect of vitamin C and E supplementation on susceptibility of plasma lipoproteins to peroxidation induced by acute smoking

1990 • 205 citations

Platelet activation by oxidatively modified low density lipoproteins

1989 • 183 citations

Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis

1991 • 170 citations

Role of endothelial cells and their products in the modification of low-density lipoproteins

1986 • 159 citations

Isolation, purification, and characterization of a lipoprotein containing apo B from the human aorta

1982 • 135 citations

Cholesterol esterification in macrophages. Stimulation by lipoproteins containing apo B isolated from human aortas.

1984 • 107 citations

Lipolysis of LDL with phospholipase A2 alters the expression of selected apoB-100 epitopes and the interaction of LDL with cells

1988 • 105 citations

Oxidation-labile subfraction of human plasma low density lipoprotein isolated by ion-exchange chromatography

1991 • 75 citations

Immunological detection of low-density lipoproteins modified by malondialdehyde in vitro or in vivo

1987 • 46 citations

Selenium in Ischaemic Heart Disease

1987 • 42 citations

Changes of apolipoprotein B molecular weight and immunoreactivity in malondialdehyde-modified low density lipoproteins.

1983 • 25 citations

Effects of oxidized low density lipoproteins on arachidonic acid metabolism in smooth muscle cells.

1990 • 22 citations

Effect of probucol on a more electronegative LDL subfraction in primary hypercholesterolemia

1990 • 4 citations

Presence and possible meaning of a more electronegative LDL in human plasma

1990 • 1 citations