Expression and activity of MMPS and their regulators in ovarian cancer

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

The origin and function of tumor-associated macrophages

1992 • 1,081 citations

Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases.

1992 • 429 citations

Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.

1993 • 428 citations

A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts.

1993 • 383 citations

Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.

1990 • 379 citations

Activity of type IV collagenases in benign and malignant breast disease

1993 • 337 citations

Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.

1992 • 333 citations

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.

1992 • 331 citations

Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue.

1990 • 323 citations

Biology of tumour metastasis

1992 • 312 citations

Distribution of myoepithelial cells and basement membrane proteins in the normal breast and in benign and malignant breast diseases.

1982 • 285 citations

Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

1993 • 283 citations

Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression.

1993 • 254 citations

Modulation by interleukin 1 and tumor necrosis factor α of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes

1990 • 247 citations

Inhibition of Collagenolytic Activity and Metastasis of Tumor Cells by a Recombinant Human Tissue Inhibitor of Metalloproteinases

1990 • 233 citations

Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.

1987 • 226 citations

Detergent-activation of latent collagenase and resolution of its component molecules

1982 • 202 citations

Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia.

1993 • 182 citations

Tumor cell stimulation of collagenase production by fibroblasts

1982 • 166 citations

Substrate specificities and activation mechanisms of matrix metalloproteinases

1991 • 164 citations

Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma.

1990 • 146 citations

Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis.

1986 • 125 citations

Stromelysin/transin and tumor progression.

1990 • 104 citations

Tumor necrosis factor bifunctionally regulates matrix metalloproteinases and tissue inhibitor of metalloproteinases (TIMP) production by human fibroblasts

1990 • 103 citations

Tumour basement membrane laminin in adenocarcinoma of rectum: An immunohistochemical study of biological and clinical significance

1986 • 93 citations

Investigation of cytokine gene expression in human colorectal cancer.

1990 • 71 citations

Bimodal relationship between invasion of the amniotic membrane and plasminogen activator activity

1990 • 45 citations