Panning for gold: genome-wide scanning for linkage in type 1 diabetes

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

1993 • 3,693 citations

A genome-wide search for human type 1 diabetes susceptibility genes

1994 • 1,294 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

Insulin-Dependent Diabetes Mellitus as an Autoimmune Disease

1994 • 818 citations

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

1996 • 794 citations

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1995 • 749 citations

Genetic Analysis of Autoimmune Disease

1996 • 739 citations

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

1996 • 638 citations

A genome–wide search for human non–insulin–dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2

1996 • 601 citations

Genetic Control of Autoimmune Diabetes in the Nod Mouse

1995 • 586 citations

Assessing the role of HLA-linked and unlinked determinants of disease.

1987 • 548 citations

The Murine Autoimmune Diabetes Model: NOD and Related Strains

1992 • 498 citations

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

1991 • 494 citations

CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

1995 • 426 citations

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1994 • 397 citations

An international two–stage genome–wide search for schizophrenia susceptibility genes

1995 • 385 citations

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

1991 • 378 citations

Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins

1995 • 357 citations

HUMAN TYPE 1 DIABETES AND THE INSULIN GENE: Principles of Mapping Polygenes

1996 • 291 citations

Mapping Genes in Diabetes: Genetic Epidemiological Perspective

1990 • 290 citations

Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping

1989 • 238 citations

Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations

1996 • 225 citations

High-resolution genetic mapping of complex traits.

1995 • 220 citations

Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31–q33

1995 • 211 citations

Comparison of statistics for candidate-gene association studies using cases and parents.

1994 • 203 citations

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus

1994 • 175 citations

Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/lty/Bcg genes on chromosome 1

1991 • 171 citations

Insulin gene region–encoded susceptibility to type 1 diabetes is not restricted to HLA–DR4–positive individuals

1992 • 138 citations

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

1996 • 129 citations

Limits of resolution of genetic linkage studies: implications for the positional cloning of human disease genes.

1994 • 121 citations

Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: application to nonobese diabetic (NOD) mouse and human insulin-dependent diabetes mellitus (IDDM).

1993 • 118 citations

Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27.

1995 • 115 citations

Familial recurrence-pattern analysis of cleft lip with or without cleft palate.

1992 • 111 citations

Markers on Distal Chromosome 2q Linked to Insulin-Dependent Diabetes Mellitus

1996 • 111 citations

Susceptibility to Insulin-Dependent Diabetes Mellitus Maps to a Locus (IDDM11) on Human Chromosome 14q24.3–q31

1996 • 99 citations

HLA and Insulin-Dependent Diabetes. A protective perspective

1992 • 94 citations

HLA and insulin gene associations with IDDM

1989 • 93 citations

A Protective Role of the Environment in the Development of Type 1 Diabetes?

1991 • 82 citations

The HOXD8 Locus (2q31) is Linked to Type I Diabetes: Interaction with Chromosome 6 and 11 Disease Susceptibility Genes

1995 • 76 citations

The Search for IDDM Susceptibility Genes: The Next Generation

1996 • 71 citations

Saturation multipoint linkage mapping of chromosome 6q in type 1 diabetes

1996 • 60 citations

Linkage and association between insulin–dependent diabetes mellitus (IDDM) susceptibility and markers near the glucokinase gene on chromosome 7

1995 • 49 citations

Mapping the diabetes polygene Idd3 on mouse Chromosome 3 by use of novel congenic strains

1995 • 41 citations

The genetics of the NOD mouse

1995 • 24 citations

Diabetic twins in Japan

1994 • 23 citations

Intrafamilial and Case-Control Association Analysis of D2S152 in Insulin-Dependent Diabetes

1995 • 18 citations

Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains

1995 • 8 citations