Contribution of Nitric Oxide Synthases 1, 2, and 3 to Airway Hyperresponsiveness and Inflammation in a Murine Model of Asthma

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1995 • 2,075 citations

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1995 • 1,454 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography

1997 • 1,294 citations

Increased amount of nitric oxide in exhaled air of asthmatics

1993 • 1,252 citations

Induction of nitric oxide synthase in asthma

1993 • 852 citations

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

1997 • 712 citations

Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients.

1996 • 588 citations

Inhaled Nitric Oxide

2004 • 502 citations

Single-breath nitric oxide measurements in asthmatic patients and smokers

1994 • 498 citations

Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock

1998 • 476 citations

Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid

1998 • 441 citations

Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase

1996 • 436 citations

National asthma education program expert panel report. Guidelines for the diagnosis and management of asthma

1991 • 397 citations

Detection of eosinophils using an eosinophil peroxidase assay. Its use as an assay for eosinophil differentiation factors

1985 • 303 citations

Evidence that part of the NANC relaxant response of guinea‐pig trachea to electrical field stimulation is mediated by nitric oxide

1991 • 300 citations

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice

1995 • 275 citations

Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins.

1997 • 275 citations

Requirement for γδ T Cells in Allergic Airway Inflammation

1998 • 268 citations

Nitric Oxide and Airway Disease

1995 • 263 citations

Pulmonary responses to bronchoconstrictor agonists in the mouse

1988 • 251 citations

Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice

1998 • 243 citations

<scp>l</scp>‐N^G‐nitro arginine inhibits non‐adrenergic, non‐cholinergic relaxations of guinea‐pig isolated tracheal smooth muscle

1990 • 230 citations

Corticosteroids decrease exhaled nitric oxide in children with acute asthma

1997 • 226 citations

Linkage of Asthma and Total Serum IgE Concentration to Markers on Chromosome 12q: Evidence from Afro-Caribbean and Caucasian Populations

1996 • 226 citations

Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure

1998 • 216 citations

Characterization of a Murine Model of Allergic Pulmonary Inflammation

1994 • 214 citations

Inducible Nitric Oxide Synthase Is Increased in Murine Lung Epithelial Cells by Cytokine Stimulation

1994 • 204 citations

Elevated nitric oxide concentrations in isolated lower airway gas of asthmatic subjects.

1996 • 191 citations

National Asthma Education Program

1990 • 176 citations

Inhibition of Allergic Airway Inflammation in Mice Lacking Nitric Oxide Synthase 2

1999 • 160 citations

Endogenous nitric oxide is decreased in asthmatic patients by an inhibitor of inducible nitric oxide synthase.

1996 • 158 citations

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.

1996 • 139 citations

Inhaled nitric oxide. A bronchodilator in mild asthmatics with methacholine-induced bronchospasm.

1996 • 139 citations

Expression and activity of nitric oxide synthases in human airway epithelium.

1997 • 129 citations

PDB2MultiGIF: A Web Tool to Create Animated Images of Molecules

1998 • 123 citations

T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice

1997 • 116 citations

CTLA4Ig Inhibits Airway Eosinophilia and Hyperresponsiveness by Regulating the Development of Th1/Th2 Subsets in a Murine Model of Asthma

1998 • 105 citations

Role of Nitric Oxide on Eosinophilic Lung Inflammation in Allergic Mice

1997 • 104 citations

Guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. National Asthma Education Program. Expert Panel Report.

1991 • 101 citations

Exhaled Nitric Oxide and Bronchial Reactivity During and After Inhaled Beclomethasone in Mild Asthma

1998 • 101 citations

Antigen-Induced Airway Hyperresponsiveness, Pulmonary Eosinophilia, and Chemokine Expression in B Cell–Deficient Mice

1999 • 99 citations

Airborne nitric oxide: Inflammatory marker and aerocrine messenger in man

1996 • 82 citations

Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice

1997 • 81 citations

Reduction of allergic airway responses in P-selectin-deficient mice

1997 • 80 citations

Exhaled Nitric Oxide Is Increased in Asthma

1995 • 72 citations

Nitric Oxide and Bronchial Hyperresponsiveness

2000 • 69 citations

The Candidate Region Approach to the Genetics of Asthma and Allergy

1997 • 64 citations

Inducible nitric oxide synthase and vascular reactivity in rat thoracic aorta: effect of aminoguanidine

1996 • 62 citations

Inducible nitric oxide synthase after sensitization and allergen challenge of Brown Norway rat lung

1997 • 59 citations

Reduction of Antigen-induced Airway Hyperreactivity and Eosinophilia in ICAM-1-deficient Mice

1998 • 58 citations

T cell activation in a murine model of asthma

1996 • 57 citations

CD23 Deficient Mice Develop Allergic Airway Hyperresponsiveness Following Sensitization with Ovalbumin

1997 • 54 citations

Allergen-induced Early and Late Asthmatic Responses Are Not Affected by Inhibition of Endogenous Nitric Oxide

1998 • 54 citations

Functional analysis of the ACTGCTGA sequence motif in the human immunodeficiency virus type-1 long terminal repeat promoter

1994 • 51 citations

On the positive charge and interface states in metal-oxide-semiconductor capacitors

1996 • 38 citations

The effect of inhaled nitric oxide in pediatric asthma.

1996 • 30 citations

Induction of calcium‐independent nitric oxide synthase by allergen challenge in sensitized rat lung in vivo

1995 • 29 citations

Inducible Nitric Oxide Synthase Is Not Required for Long-Term Vaccine-Based Immunity AgainstToxoplasma gondii

1998 • 28 citations

Inducible Nitric Oxide Synthase mRNA and Immunoreactivity in the Lungs of Rats Eight Hours after Antigen Challenge

1997 • 23 citations

Effect of nitric oxide inhalation on respiratory system resistance in chronic obstructive pulmonary disease

1996 • 20 citations

In-vitro Bronchorelaxing Effects of Novel Nitric Oxide Donors GEA 3268 and GEA 5145 in Guinea-pigs and Rats

1996 • 16 citations

Characterization of the Antigen-Presenting Cell and T Cell Requirements for Induction of Pulmonary Eosinophilia in a Murine Model of Asthma

1996 • 13 citations

Inhaled nitric oxide attenuates bronchoconstriction in canine peripheral airways.

1996 • 10 citations

Pulmonary eosinophilia and inflammation in allergic mice.

1998 • 2 citations