Effect of interleukin 17 on proteoglycan degradation in murine knee joints

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

1999 • 1,660 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

1999 • 943 citations

CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene.

1993 • 751 citations

Enhancing Effect of IL-17 on IL-1-Induced IL-6 and Leukemia Inhibitory Factor Production by Rheumatoid Arthritis Synoviocytes and Its Regulation by Th2 Cytokines

1998 • 451 citations

IL-17 Is Produced by Some Proinflammatory Th1/Th0 Cells But Not by Th2 Cells

1999 • 415 citations

Interleukin-17-induced Gene Expression in Articular Chondrocytes Is Associated with Activation of Mitogen-activated Protein Kinases and NF-κB

1998 • 386 citations

Shift toward T lymphocytes with a T helper 1 cytokine‐secretion profile in the joints of patients with rheumatoid arthritis

1996 • 299 citations

MOLECULAR CHARACTERIZATION OF THE HUMAN INTERLEUKIN (Il)-17 RECEPTOR

1997 • 282 citations

Th1/Th2 cytokine balance in arthritis

1997 • 259 citations

Interleukin‐17 up‐regulation of nitric oxide production in human osteoarthritis cartilage

1997 • 183 citations

Interleukin-17: A New Bone Acting Cytokine In Vitro

1999 • 167 citations

Effects of murine recombinant interleukin 1 on synovial joints in mice: measurement of patellar cartilage metabolism and joint inflammation.

1990 • 138 citations

Mouse IL-17: A Cytokine Preferentially Expressed by αβTCR+CD4—CD8— T Cells

1996 • 138 citations

In vivo effects of interleukin‐1 on articular cartilage. Prolongation of proteoglycan metabolic disturbances in old mice

1991 • 75 citations

The Th1/Th2 cytokine balance in arthritis

1998 • 67 citations

Quantitation of glycosaminoglycan metabolism in anatomically intact articular cartilage of the mouse patella: in vitro and in vivo studies with 35S-sulfate, 3H-glucosamine, and 3H-acetate

1986 • 44 citations

Quantitation of arthritis by99mTc-uptake measurements in the mouse knee-joint: correlation with histological joint inflammation scores

1984 • 44 citations

Effects of murine recombinant interleukin 1 on intact homologous articular cartilage: a quantitative and autoradiographic study.

1988 • 34 citations

Direct effect of murine rIL-1 on cartilage metabolismin vivo

1989 • 11 citations