Successful Prospective Prediction of Type 1 Diabetes in Schoolchildren Through Multiple Defined Autoantibodies

Statistical Inference

1990 • 5,570 citations

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1990 • 1,955 citations

Quantification of the Relationship Between Insulin Sensitivity and β-Cell Function in Human Subjects: Evidence for a Hyperbolic Function

1993 • 1,391 citations

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1983 • 1,078 citations

Worldwide increase in incidence of Type I diabetes - the analysis of the data on published incidence trends

1999 • 906 citations

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1995 • 749 citations

Assessment of Diagnostic Tests When Disease Verification is Subject to Selection Bias

1983 • 668 citations

Prediction of IDDM in the General Population: Strategies Based on Combinations of Autoantibody Markers

1997 • 425 citations

Newborn screening for HLA markers associated with IDDM: Diabetes Autoimmunity Study in the Young (DAISY)

1996 • 416 citations

Feasibility of genetic and immunological prediction of Type I diabetes in a population-based birth cohort

2001 • 336 citations

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function

1993 • 320 citations

Molecular Cloning and Identification of a Receptor-Type Protein Tyrosine Phosphatase, IA-2, from Human Insulinoma

1994 • 317 citations

Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases.

1994 • 308 citations

Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children.

1995 • 255 citations

Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.

1995 • 239 citations

A Novel Micro-assay for Insulin Autoantibodies

1997 • 238 citations

The epidemiology of diabetes in Swedish children 0?14 years ? a six-year prospective study

1985 • 218 citations

Antiislet autoantibodies usually develop sequentially rather than simultaneously.

1996 • 201 citations

Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers

1997 • 149 citations

Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives.

1994 • 134 citations

Linkage Analysis of 49 High-Risk Families Does Not Support a Common Familial Prostate Cancer—Susceptibility Gene at 1q24-25

1997 • 124 citations

Cloning and Expression of IDDM-Specific Human Autoantigens

1992 • 118 citations

Perinatal Autoimmunity in Offspring of Diabetic Parents: The German Multicenter BABY-DIAB Study: Detection of Humoral Immune Responses to Islet Antigens in Early Childhood

1996 • 118 citations

Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes

2000 • 118 citations

Predictive value of islet cell and insulin autoantibodies for Type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children

1992 • 115 citations

THE INCIDENCE OF DIABETES MELLITUS IN SWEDISH CHILDREN 0–14 YEARS OF AGE

1982 • 95 citations

TEN-YEAR FOLLOW-UP STUDY OF ISLET-CELL ANTIBODIES AND CHILDHOOD DIABETES MELLITUS

1989 • 89 citations

Progression to diabetes in relatives with islet autoantibodies. Is it inevitable?

1999 • 73 citations

Islet Cell Antibodies as Predictive Markers for IDDM in Children With High Background Incidence of Disease

1990 • 72 citations

The Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies

1991 • 72 citations

Validity of Screening for Individuals at Risk for Type I Diabetes by Combined Analysis of Antibodies to Recombinant Proteins

1997 • 70 citations

Analysis of a microsatellite polymorphism of the cytotoxic T-lymphocyte antigen-4 gene in patients with vitiligo

1999 • 68 citations

Cloning and expression of IDDM-specific human autoantigens

1992 • 43 citations

Epidemiology and Immunogenetic Background of Islet Cell Antibody–Positive Nondiabetic Schoolchildren: Ulm-Frankfurt Population Study

1991 • 42 citations

Value of antibodies to GAD65 combined with islet cell cytoplasmic antibodies for predicting IDDM in a childhood population

1994 • 42 citations

A novel high-throughput method for accurate, rapid, and economical measurement of multiple Type 1 diabetes autoantibodies

2000 • 41 citations

High Genetic Risk for IDDM in the Pacific Northwest: First Report From the Washington State Diabetes Prediction Study

1994 • 36 citations

Islet cell antibodies in normal French schoolchildren

1992 • 35 citations

Islet autoantibodies in the prediction of diabetes in school children

2001 • 30 citations

Perinatal autoimmunity in offspring of diabetic parents. The German Multicenter BABY-DIAB study: detection of humoral immune responses to islet antigens in early childhood

1996 • 28 citations

Islet cell antibodies as predictive markers for IDDM in children with high background incidence of disease

1990 • 26 citations

Immunogenetic Determinants and Prediction of IDDM in French Schoolchildren

1995 • 26 citations

The development of a World Health Organisation international standard for islet cell antibodies: the aims and design of an international collaborative study

1999 • 25 citations

Contribution of Glutamate Decarboxylase Antibodies to the Reactivity of Islet Cell Cytoplasmic Antibodies

1994 • 24 citations

Primary and secondary prevention strategies of pre-type 1 diabetes. Potentials and pitfalls.

1999 • 18 citations

Epidemiology and immunogenetic background of islet cell antibody--positive nondiabetic schoolchildren. Ulm-Frankfurt population study

1991 • 13 citations

Immunogenetic determinants and prediction of IDDM in French schoolchildren

1995 • 5 citations

Insulin autoantibodies (IAA) may cause false positive islet cell antibody (ICA) results in the indirect immunofluorescence test.

1988 • 4 citations