Linkage Analysis of 49 High-Risk Families Does Not Support a Common Familial Prostate Cancer—Susceptibility Gene at 1q24-25

Parametric and nonparametric linkage analysis: a unified multipoint approach.

1996 • 2,905 citations

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

Cancer statistics, 1996

1996 • 1,807 citations

Analysis of Human Genetic Linkage.

1992 • 1,770 citations

Faster sequential genetic linkage computations.

1993 • 1,378 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14

1992 • 941 citations

Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search

1996 • 834 citations

Mendelian inheritance of familial prostate cancer.

1992 • 803 citations

Family history and the risk of prostate cancer

1990 • 729 citations

Analysis of Human Genetic Linkage.

1987 • 709 citations

Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

1992 • 612 citations

Hereditary Prostate Cancer: Epidemiologic and Clinical Features

1993 • 610 citations

Analysis of Human Genetic Linkage

1992 • 555 citations

The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer.

1995 • 492 citations

Allelic loss of chromosomes 16q and 10q in human prostate cancer.

1990 • 456 citations

p53 is mutated in a subset of advanced-stage prostate cancers.

1993 • 377 citations

Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer.

1993 • 364 citations

Reduction of E-cadherin levels and deletion of the alpha-catenin gene in human prostate cancer cells.

1993 • 294 citations

Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss.

1996 • 269 citations

Absence of Linkage of Chromosome 21q21 Markers to Familial Alzheimer's Disease

1988 • 245 citations

Mutation of the MXI1 gene in prostate cancer

1995 • 207 citations

Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer.

1995 • 171 citations

Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1.

1994 • 160 citations

An uncertain role for p53 gene alterations in human prostate cancers.

1996 • 131 citations

Physical Mapping of Chromosome 8p22 Markers and Their Homozygous Deletion in a Metastatic Prostate Cancer

1996 • 108 citations

Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes.

1995 • 107 citations

Detecting linkage for genetically heterogeneous diseases and detecting heterogeneity with linkage data.

1986 • 85 citations

Differences in cancer incidence, mortality, and survival between African Americans and whites.

1995 • 73 citations

Evidence for a Tumor Suppressor Gene Distal to BRCA1 in Prostate Cancer

1996 • 64 citations

P53 mutations and loss of heterozygosity on chromosomes 8p, 16q, 17p, and 18q are confined to advanced prostate cancer.

1994 • 47 citations

Tumor suppressor genes in prostatic oncogenesis.

1994 • 36 citations

Metastasis suppressor genes for prostate cancer

1996 • 30 citations