An Essential Domain of the c-Myc Protein Interacts with a Nuclear Factor That Is Also Required for E1A-Mediated Transformation

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1993 • 875 citations

myc FUNCTION AND REGULATION

1992 • 790 citations

The ornithine decarboxylase gene is a transcriptional target of c-Myc.

1993 • 759 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis.

1993 • 677 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

Myc and Max proteins possess distinct transcriptional activities

1992 • 478 citations

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

1992 • 458 citations

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

1987 • 457 citations

An amino-terminal c-myc domain required for neoplastic transformation activates transcription.

1990 • 413 citations

Dominant negative MYC blocks transformation by ABL oncogenes

1992 • 410 citations

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

1990 • 397 citations

Binding of myc proteins to canonical and noncanonical DNA sequences.

1993 • 375 citations

The role of c-myc in cell growth

1993 • 365 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

1991 • 326 citations

New light on Myc and Myb. Part I. Myc.

1990 • 325 citations

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.

1989 • 283 citations

Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter.

1989 • 262 citations

A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.

1990 • 253 citations

Binding and Suppression of the Myc Transcriptional Activation Domain by p107

1994 • 242 citations

Ornithine Decarboxylase Is a Mediator of c-Myc-Induced Apoptosis

1994 • 238 citations

Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers.

1992 • 230 citations

Transcriptional and Transforming Activities of the Adenovirus E1A Proteins

1991 • 187 citations

c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif.

1993 • 186 citations

Determination of the c-MYC DNA-binding site.

1991 • 181 citations

TFEB has DNA-binding and oligomerization properties of a unique helix-loop-helix/leucine-zipper family.

1991 • 174 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

1993 • 146 citations

Myc and Max function as a nucleoprotein complex

1992 • 143 citations

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants.

1992 • 129 citations

An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-myc.

1994 • 127 citations

Sequence-Specific Transcriptional Activation by Myc and Repression by Max

1993 • 124 citations

The retinoblastoma gene and gene product.

1992 • 111 citations

Max and c-Myc/Max DNA-binding activities in cell extracts.

1992 • 94 citations

max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors.

1992 • 92 citations

Immortalization by c-myc, H-ras, and Ela oncogenes induces differential cellular gene expression and growth factor responses.

1987 • 82 citations

Intracellular Association of the Protein Product of the c-myc Oncogene with the TATA-Binding Protein

1994 • 78 citations

Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.

1987 • 78 citations

DNA binding activities of c-Myc purified from eukaryotic cells.

1992 • 57 citations

Mutational analysis of Max: role of basic, helix-loop-helix/leucine zipper domains in DNA binding, dimerization and regulation of Myc-mediated transcriptional activation.

1992 • 53 citations

Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes.

1987 • 52 citations

Yeast GCN4 as a probe for oncogenesis by AP-1 transcription factors: transcriptional activation through AP-1 sites is not sufficient for cellular transformation.

1992 • 48 citations

B-myc inhibits neoplastic transformation and transcriptional activation by c-myc.

1993 • 47 citations

Complementation of transforming domains in E1a/myc chimaeras

1991 • 22 citations

E1A products of adenoviruses reduce the expression of cellular proliferation-associated genes.

1988 • 21 citations

The transcription activation domains of v-Myc and VP16 interact with common factors required for cellular transformation and proliferation.

1994 • 7 citations