Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism.

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

1999 • 2,458 citations

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress

1999 • 1,494 citations

Identification of genetic polymorphisms at the glutathione S- transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer

1997 • 749 citations

Molecular Cloning, Characterization, and Expression in Escherichia coli of Full-length cDNAs of Three Human Glutathione S-Transferase Pi Gene Variants

1997 • 716 citations

Detoxication of base propenals and other alpha,beta-unsaturated aldehyde products of radical reactions and lipid peroxidationby human glutathione transferases.

1994 • 412 citations

Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study

2000 • 208 citations

Primary chemotherapy in breast invasive carcinoma: predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi

1996 • 196 citations

Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.

1994 • 161 citations

Susceptibility to esophageal cancer and genetic polymorphisms in glutathione S-transferases T1, P1, and M1 and cytochrome P450 2E1.

1998 • 146 citations

A pilot study of pi-class glutathione S-transferase expression in breast cancer: correlation with estrogen receptor expression and prognosis in node-negative breast cancer.

1993 • 114 citations

Differential Catalytic Efficiency of Allelic Variants of Human GlutathioneS-Transferase Pi in Catalyzing the Glutathione Conjugation of Thiotepa

1999 • 111 citations

Glutathione S-transferase expression in benign and malignant ovarian tumours

1993 • 102 citations

Expression of p53, Glutathione S -Transferase- , and Bcl-2 Proteins and Benefit From Adjuvant Radiotherapy in Breast Cancer

1997 • 99 citations

Expression of Glutathione S-Transferase-π in Human Ovarian Cancer as an Indicator of Resistance to Chemotherapy

1994 • 97 citations

Expression of glutathione S-transferases and cytochrome P450 in normal and tumor breast tissue

1990 • 92 citations

Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status and clinicopathological variables in breast cancer patients

1998 • 89 citations

Response to adjuvant chemotherapy in primary breast cancer: no correlation with expression of glutathione S-transferases

1993 • 30 citations

Relation of glutathione S-transferase alpha and mu isoforms to response to therapy in human breast cancer.

1997 • 24 citations