Ontogeny and sexual dimorphic expression of mouse type 2 11β-hydroxysteroid dehydrogenase

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Fetal and placental size and risk of hypertension in adult life.

1990 • 1,737 citations

Mineralocorticoid Action: Target Tissue Specificity Is Enzyme, Not Receptor, Mediated

1988 • 1,607 citations

LOCALISATION OF 11β-HYDROXYSTEROID DEHYDROGENASE—TISSUE SPECIFIC PROTECTOR OF THE MINERALOCORTICOID RECEPTOR

1988 • 1,047 citations

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.

1995 • 926 citations

Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme

1994 • 707 citations

Human hypertension caused by mutations in the kidney isozyme of 11β–hydroxysteroid dehydrogenase

1995 • 621 citations

Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?

1993 • 554 citations

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

1991 • 434 citations

Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle.

1988 • 420 citations

11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta- reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations.

1995 • 301 citations

The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development.

1996 • 281 citations

Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis.

1995 • 278 citations

Urinary free cortisone and the assessment of 11β‐hydroxysteroid dehydrogenase activity in man

1996 • 269 citations

Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform.

1993 • 263 citations

NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney

1994 • 246 citations

Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene

1996 • 235 citations

Regulation of the Primate Fetal Adrenal Cortex*

1990 • 209 citations

A mutation in the HSD11B2 gene in a family with apparent mineralocorticoid excess.

1995 • 200 citations

Human kidney 11 beta-hydroxysteroid dehydrogenase is a high affinity nicotinamide adenine dinucleotide-dependent enzyme and differs from the cloned type I isoform.

1994 • 176 citations

Licorice inhibits 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and potentiates glucocorticoid hormone action.

1993 • 158 citations

11 beta-Hydroxysteroid dehydrogenase alleviates glucocorticoid-mediated inhibition of steroidogenesis in rat Leydig cells.

1994 • 149 citations

Regulation of 11β-hydroxysteroid dehydrogenase by sex steroids in vivo: further evidence for the existence of a second dehydrogenase in rat kidney

1993 • 117 citations

Type 2 11 beta-hydroxysteroid dehydrogenase in human fetal tissues.

1994 • 116 citations

Cloning, expression, and tissue distribution of the rat nicotinamide adenine dinucleotide-dependent 11 beta-hydroxysteroid dehydrogenase.

1995 • 114 citations

Type 2 11β-hydroxysteroid dehydrogenase in foetal and adult life

1995 • 108 citations

Regulation of 1lβ-Hydroxysteroid Dehydrogenase Activity in the Baboon Placenta by Estrogen*

1990 • 92 citations

Epithelial cell localization of type 2 11 beta-hydroxysteroid dehydrogenase in rat and human colon.

1994 • 84 citations

Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney.

1995 • 83 citations

Cloning, sequencing and tissue-distribution of mouse 11β-hydroxysteroid dehydrogenase-1 cDNA

1995 • 62 citations

Expression cloning of the aldosterone target cell-specific 11 beta-hydroxysteroid dehydrogenase from rabbit collecting duct cells.

1995 • 60 citations

The purification of 11β-hydroxysteroid dehydrogenase from mouse liver microsomes

1994 • 52 citations

Sex- and tissue- specific regulation of 11β-hydroxysteroid dehydrogenase mRNA

1995 • 46 citations

Rat 11β-hydroxysteroid dehydrogenase type 2 enzyme is expressed at low levels in the placenta and is modulated by adrenal steroids in the kidney

1996 • 45 citations

Differential expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in the developing ovine fetal liver and kidney

1995 • 33 citations

11 beta-hydroxysteroid dehydrogenase and corticosteroid hormone receptors in the rat colon

1993 • 17 citations