NKG2D function protects the host from tumor initiation

IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

2001 • 2,658 citations

Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

1995 • 2,437 citations

Molecular identification of a danger signal that alerts the immune system to dying cells

2003 • 1,649 citations

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

2000 • 1,632 citations

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

2002 • 1,529 citations

Roles of the NKG2D immunoreceptor and its ligands

2003 • 1,297 citations

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

2001 • 1,190 citations

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

2001 • 1,036 citations

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

1996 • 1,010 citations

Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

1999 • 1,006 citations

mRNA Is an Endogenous Ligand for Toll-like Receptor 3

2004 • 994 citations

Regulation of Cutaneous Malignancy by γδ T Cells

2001 • 945 citations

Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages

2000 • 864 citations

Differential Tumor Surveillance by Natural Killer (Nk) and Nkt Cells

2000 • 812 citations

A fresh look at tumor immunosurveillance and immunotherapy

2001 • 723 citations

Retinoic Acid Early Inducible Genes Define a Ligand Family for the Activating NKG2D Receptor in Mice

2000 • 694 citations

The Role of the NKG2D Immunoreceptor in Immune Cell Activation and Natural Killing

2002 • 634 citations

Increased Susceptibility to Tumor Initiation and Metastasis in TNF-Related Apoptosis-Inducing Ligand-Deficient Mice

2002 • 608 citations

Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia

2003 • 510 citations

Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.

2002 • 509 citations

Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development

2002 • 447 citations

DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.

1991 • 430 citations

NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma

2001 • 345 citations

NKG2D Blockade Prevents Autoimmune Diabetes in NOD Mice

2004 • 293 citations

Perforin Is a Major Contributor to NK Cell Control of Tumor Metastasis

1999 • 290 citations

Cutting Edge: Murine UL16-Binding Protein-Like Transcript 1: A Newly Described Transcript Encoding a High-Affinity Ligand for Murine NKG2D

2002 • 271 citations

Ligands for natural killer cell receptors: redundancy or specificity

2001 • 246 citations

Functions of nonclassical MHC and non-MHC-encoded class I molecules

1999 • 211 citations

Cutting Edge: Toll-Like Receptor Signaling in Macrophages Induces Ligands for the NKG2D Receptor

2004 • 203 citations

MICA and MICB genes: can the enigma of their polymorphism be resolved?

2001 • 194 citations

Effects of Human Cytomegalovirus Infection on Ligands for the Activating NKG2D Receptor of NK Cells: Up-Regulation of UL16-Binding Protein (ULBP)1 and ULBP2 Is Counteracted by the Viral UL16 Protein

2003 • 182 citations

Cutting Edge: Tumor Rejection Mediated by NKG2D Receptor-Ligand Interaction Is Dependent upon Perforin

2002 • 181 citations

NKG2D Recognition and Perforin Effector Function Mediate Effective Cytokine Immunotherapy of Cancer

2004 • 169 citations

Expression of Stress-induced MHC Class I Related Chain Molecules on Human Melanoma

2002 • 168 citations

α-Galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis

2003 • 149 citations

Effect of interleukin 12 on tumor induction by 3-methylcholanthrene.

1996 • 136 citations

Costimulation of Multiple NK Cell Activation Receptors by NKG2D

2002 • 106 citations