The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization

1998 • 4,811 citations

New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

1994 • 2,554 citations

A Genome-Wide Transcriptional Analysis of the Mitotic Cell Cycle

1998 • 2,102 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

1998 • 652 citations

The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast.

1994 • 502 citations

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

1998 • 453 citations

Regulation of DNA-replication origins during cell-cycle progression

1998 • 415 citations

Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins

1993 • 376 citations

Enzymes and Reactions at the Eukaryotic DNA Replication Fork

1997 • 328 citations

Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual

1994 • 296 citations

[14] Cloning genes by complementation in yeast

1991 • 266 citations

HOP1: a yeast meiotic pairing gene.

1989 • 250 citations

A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.

1992 • 235 citations

Effect of DNA lesions on transcription elongation

1999 • 229 citations

Ribonuclease H. An Enzyme Degrading the RNA Moiety of DNA-RNA Hybrids

1970 • 217 citations

Identification of the Genes Encoding Mn²⁺-Dependent RNase HII and Mg²⁺-Dependent RNase HIII from Bacillus subtilis: Classification of RNases H into Three Families

1998 • 165 citations

Properties of Cloned and Expressed Human RNase H1

1999 • 161 citations

Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease

1999 • 152 citations

Isolation and characterization of a second RNase H (RNase HII) of Escherichia coli K-12 encoded by the rnhB gene.

1990 • 141 citations

Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA

1993 • 113 citations

Ribonuclease H from K562 human erythroleukemia cells. Purification, characterization, and substrate specificity.

1991 • 113 citations

Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae

1986 • 101 citations

G2 / M checkpoint genes of Saccharomyces cerevisiae : further evidence for roles in DNA replication and / or repair

1997 • 92 citations

Junction ribonuclease: An activity in Okazaki fragment processing

1998 • 81 citations

Isolation of RNase H Genes That Are Essential for Growth of Bacillus subtilis 168

1999 • 79 citations

Purification, subunit structure, and serologicai analysis of calf thymus ribonuclease H I.

1980 • 74 citations

Distinct Ribonuclease H Activities in Calf Thymus

1975 • 71 citations

Ribonuclease H: from discovery to 3D structure.

1990 • 70 citations

6 Roles of Ribonuclease H in Reverse Transcription

1993 • 63 citations

Selective cloning of genes encoding RNase H from Salmonella typhimurium, Saccharomyces cerevisiae and Escherichia coli rnh mutant

1991 • 62 citations

Cloning, Expression, and Mapping of Ribonucleases H of Human and Mouse Related to Bacterial RNase HI

1998 • 60 citations

Ribonuclease H Levels during the Response of Bovine Lymphocytes to Concanavalin A

1977 • 59 citations

[54] Analysis of chromosome segregation in Saccharomyces cerevisiae

1991 • 57 citations

Isolation and mapping of a mutation in Escherichia coli with altered levels of ribonuclease H

1980 • 55 citations

Creation and Removal of Embedded Ribonucleotides in Chromosomal DNA during Mammalian Okazaki Fragment Processing

1997 • 54 citations

Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication

1998 • 54 citations

Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII¹

1998 • 47 citations

A common 40 amino acid motif in eukaryotic RNases H1 and caulimovirus ORF VI proteins binds to duplex RNAs

1998 • 44 citations

The non-RNase H domain of Saccharomyces cerevisiae RNase H1 binds double-stranded RNA: magnesium modulates the switch between double-stranded RNA binding and RNase H activity.

1995 • 37 citations

Isolation and characterization of two enzymatic activities from chick embryos which degrade double-stranded RNA.

1977 • 36 citations

Characterization and subcellular localization of ribonuclease H activities from Xenopus laevis oocytes.

1994 • 29 citations

Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene

1999 • 29 citations

Cloning, Subcellular Localization and Functional Expression of Human RNase HII

1998 • 25 citations

Synchronous cell growth occurs upon synchronizing the two regulatory steps of the Saccharomyces cerevisiae cell cycle

1984 • 20 citations

Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle

1997 • 16 citations

Ribonuclease H Renaturation Gel Assay Using a Fluorescent-Labeled Substrate

1997 • 12 citations

Reaction-rate spectrophotometric method for analysis of gossypol in cottonseed extracts

1982 • 8 citations