Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

A Method for Gene Disruption That Allows Repeated Use of URA3 Selection in the Construction of Multiply Disrupted Yeast Strains

1987 • 887 citations

A Novel Mutation Avoidance Mechanism Dependent on S. cerevisiae RAD27 Is Distinct from DNA Mismatch Repair

1997 • 434 citations

Identification and characterization of Saccharomyces cerevisiae EXO1 , a gene encoding an exonuclease that interacts with MSH2

1997 • 382 citations

Enzymes and Reactions at the Eukaryotic DNA Replication Fork

1997 • 328 citations

DNA REPAIR GENES AND PROTEINS OF SACCHAROMYCES CEREVISIAE

1993 • 301 citations

Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.

1994 • 275 citations

Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

1995 • 264 citations

Reconstitution of Yeast Nucleotide Excision Repair with Purified Rad Proteins, Replication Protein A, and Transcription Factor TFIIH

1995 • 242 citations

A Role for Exonuclease I from S. pombe in Mutation Avoidance and Mismatch Correction

1995 • 202 citations

Evidence for Involvement of Yeast Proliferating Cell Nuclear Antigen in DNA Mismatch Repair

1996 • 200 citations

Repeat expansion — all in flap?

1997 • 198 citations

Calf 5′ to 3′ Exo/Endonuclease Must Slide from a 5′ End of the Substrate to Perform Structure-specific Cleavage

1995 • 196 citations

Requirement of the Yeast RTH1 5′ to 3′ Exonuclease for the Stability of Simple Repetitive DNA

1995 • 195 citations

Exonuclease I of Saccharomyces cerevisiae Functions in Mitotic Recombination In Vivo and In Vitro

1997 • 190 citations

Conditional Lethality of Null Mutations in RTH1 That Encodes the Yeast Counterpart of a Mammalian 5′- to 3′-Exonuclease Required for Lagging Strand DNA Synthesis in Reconstituted Systems

1995 • 168 citations

A Conditional Lethal Mutant of Escherichia coli K12 Defective in the 5′ → 3′ Exonuclease Associated with DNA Polymerase I

1974 • 145 citations

Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease

1993 • 143 citations

Genetic control of microsatellite stability

1997 • 135 citations

Human RAD2 Homolog 1 5′- to 3′-Exo/Endonuclease Can Efficiently Excise a Displaced DNA Fragment Containing a 5′-Terminal Abasic Lesion by Endonuclease Activity

1996 • 64 citations

Reconstitution of TFIIH and Requirement of Its DNA Helicase Subunits, Rad3 and Rad25, in the Incision Step of Nucleotide Excision Repair

1996 • 64 citations

Structure-specific Nuclease Activity in Yeast Nucleotide Excision Repair Protein Rad2

1995 • 57 citations

Mechanism of Tracking and Cleavage of Adduct-damaged DNA Substrates by the Mammalian 5′- to 3′-Exonuclease/Endonuclease RAD2 Homologue 1 or Flap Endonuclease 1

1996 • 45 citations

Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes

1997 • 27 citations

Molecular Cloning of a Gene,DHS1, Which Complements a Drug-hypersensitive Mutation of the YeastSaccharomyces cerevisiae

1994 • 8 citations