Effects of the new somatostatin analogue (BIM 23014) on blood glucose homeostasis in normal men

Treatment of the Malignant Carcinoid Syndrome

1986 • 852 citations

GROWTH-HORMONE RELEASE-INHIBITING HORMONE IN GASTROINTESTINAL AND PANCREATIC D CELLS

1975 • 520 citations

INHIBITION OF INSULIN SECRETION BY SOMATOSTATIN

1973 • 455 citations

Long-Term Treatment of Acromegaly with the Somatostatin Analogue SMS 201–995

1985 • 396 citations

Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

1975 • 335 citations

Physiological role of somatostatin in the control of growth hormone and thyrotropin secretion

1976 • 241 citations

Long-term Treatment of 189 Acromegalic Patients With the Somatostatin Analog Octreotide

1991 • 234 citations

Two Types of Somatostatin Receptors Differentiated by Cyclic Somatostatin Analogs

1985 • 228 citations

Physiological roles of somatocrinin and somatostatin in the regulation of growth hormone secretion

1982 • 198 citations

Evidence for two somatostatin-14 receptor types in rat brain cortex

1984 • 179 citations

Measurement of growth hormone-releasing hormone and somatostatin in hypothalamic-portal plasma of unanesthetized sheep. Spontaneous secretion and response to insulin-induced hypoglycemia.

1990 • 169 citations

SOMATOSTATINERGIC NEURONS IN ANTERIOR HYPOTHALAMUS: IMMUNOHISTOCHEMICAL LOCALIZATION¹

1976 • 167 citations

Chemistry and Pharmacology of SMS 201-995, a Long-Acting Octapeptide Analogue of Somatostatin

1986 • 157 citations

Treatment of patients with pancreatic endocrine tumours using a new long-acting somatostatin analogue symptomatic and peptide responses.

1985 • 157 citations

Medical Treatment of Acromegaly with SMS 201-995, a Somatostatin Analog: A Comparison with Bromocriptine*

1987 • 132 citations

Octreotide

1989 • 119 citations

Endocrine profile of a long-acting somatostatin derivative SMS 201–995. Study in normal volunteers following subcutaneous administration

1986 • 115 citations

Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis.

1975 • 104 citations

Somatostatin analogue (SMS 201-995) in the management of gastroenteropancreatic tumors and diarrhea syndromes

1986 • 96 citations

Treatment with a Somatostatin Analog Decreases Pancreatic B-Cell and Whole Body Sensitivity to Glucose*

1990 • 95 citations

SPECIFIC HIGH AFFINITY BINDING SITES FOR SOMATOSTATIN-28 ON PANCREATIC 6-CELLS:DIFFERENCES WITH BRAIN SOMATOSTATIN RECEPTORS1

1982 • 82 citations

Dose-Response Study and Long Term Effect of the Somatostatin Analog Octreotide in Patients with Therapy-Resistant Acromegaly*

1989 • 80 citations

Effect of Somatostatin on Plasma Glucose and Insulin Responses to Glucagon and Tolbutamide in Man

1974 • 80 citations

The interaction of growth hormone releasing hormone and somatostatin in the generation of a GH pulse in man

1991 • 69 citations

Effect of one year continuous subcutaneous infusion of a somatostatin analogue, octreotide, on early retinopathy, metabolic control and thyroid function in Type I (insulin-dependent) diabetes mellitus

1990 • 68 citations

Differential Binding of Somatostatin Agonists to Somatostatin Receptors in Brain and Adenohypophysis

1987 • 67 citations

EFFECTS OF SOMATOSTATIN ANALOGUE SMS 201–995 IN NORMAL MAN

1986 • 60 citations

Somatostatin receptor subtypes in the clonal anterior pituitary cell lines AtT-20 and GH3.

1988 • 55 citations

Prolonged secretion of prolactin in response to thyrotrophin-releasing hormone after hypothalamo-pituitary disconnection in the ewe

1986 • 49 citations

Osmiophilic Reagents in Electronmicroscopic Histocytochemistry

1979 • 48 citations

The Effect of Oral Omeprazole on Gastric Acid and Pepsin Secretion

1986 • 48 citations

Octapeptide analogs of somatostatin exhibiting greatly enhanced in vivo and in vitro inhibition of growth hormone secretion in the rat

1985 • 41 citations

Continuous subcutaneous octreotide infusion markedly suppresses IGF-I levels whilst only partially suppressing GH secretion in diabetics with retinopathy

1989 • 41 citations

24-Hour Studies of the Effects of Somatostatin on the Levels of Plasma Growth Hormone, Glucagon, and Glucose in Normal Subjects and Juvenile Diabetics

1978 • 40 citations

Effect of Diosmectite on Intestinal Permeability Changes in Acute Diarrhea

1992 • 40 citations

Effects of the Somatostatin Analog BIM 23014 on the Secretion of Growth Hormone, Thyrotropin, and Digestive Peptides in Normal Men

1989 • 39 citations

Somatostatin desensitization in rat anterior pituitary cells

1984 • 35 citations

24-hour studies of the effects of somatostatin on the levels of plasma growth hormone, glucagon, and glucose in normal subjects and juvenile diabetics

1978 • 26 citations

Immunohistochemical Localization of Somatostatin

1980 • 26 citations

Somatostatin Impairs Clearance of Exogenous Insulin in Humans

1987 • 25 citations

Effects of Somatostatin and SMS 201-995 on Carbohydrate Metabolism in Normal Man

1986 • 25 citations

The effect of a long‐acting somatostatin analogue (SMS 201–995) on intermediary metabolism and gut hormones after a test meal in normal subjects

1987 • 18 citations

Multiple subcutaneous injections of somatostatin induce tachyphylaxis of the suppression of plasma insulin, but not glucagon, in the rat

1982 • 14 citations

Somatostatin impairs clearance of exogenous insulin in humans

1987 • 10 citations

Exogenous Somatostatin Raises Plasma Insulin Levels in Patients with Insulin-Dependent Diabetes Mellitus

1990 • 6 citations