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The interaction of growth hormone releasing hormone and somatostatin in the generation of a GH pulse in man

Data up to Jan 2025

Published1991
Citations69
References51

Total Citations Per Year

Abstract

References (51)

Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic Rats

1963 • 2,254 citations

Patterns of Growth Hormone-Eeleasing Factor and Somatostatin Secretion into the Hypophysial-Portal Circulation of the Rat

1985 • 534 citations

The Interrelationship of Growth Hormone (GH)-Releasing Factor and Somatostatin in Generation of the Ultradian Rhythm of GH Secretion*

1984 • 524 citations

A summation technique for the detection of small evoked potentials

1954 • 486 citations

ACTION OF GROWTH-HORMONE-RELEASE INHIBITORY HORMONE IN HEALTHY MEN AND IN ACROMEGALY

1973 • 288 citations

Intravenous growth hormone: growth responses to patterned infusions in hypophysectomized rats

1985 • 282 citations

Analyses of 24-Hour Growth Hormone Profiles in Children: Relation to Growth*

1988 • 256 citations

THE RELATIONSHIP BETWEEN HEIGHT VELOCITY AND GROWTH HORMONE SECRETION IN SHORT PREPUBERTAL CHILDREN

1987 • 182 citations

Pulsatile growth hormone secretion in normal man during a continuous 24-hour infusion of human growth hormone releasing factor (1-40). Evidence for intermittent somatostatin secretion.

1985 • 177 citations

Association between Plasma Level of Growth Hormone and Sex Differentiation of Hepatic Steroid Metabolism in the Rat*

1982 • 171 citations

Measurement of growth hormone-releasing hormone and somatostatin in hypothalamic-portal plasma of unanesthetized sheep. Spontaneous secretion and response to insulin-induced hypoglycemia.

1990 • 169 citations

Extrahypothalamic Growth-Hormone-Releasing Factor (GRF) Secretion Is a Rare Cause of Acromegaly: Plasma GRF Levels in 177 Acromegalic Patients*

1984 • 137 citations

The rebound release of growth hormone (GH) following somatostatin infusion in rats involves hypothalamic GH-releasing factor release

1988 • 113 citations

Pulsatile, Synchronous Basal Insulin and Glucagon Secretion in Man

1982 • 111 citations

The Effects of Growth Hormone (GH)-Releasing Peptides on GH Secretion in Perifused Pituitary Cells of Adult Male Rats*

1984 • 106 citations

Circumstantial evidence for a role of the secretory pattern of growth hormone in control of body growth

1982 • 104 citations

Desensitization to Growth Hormone-Releasing Factor (GRF) Is Associated with Down-Regulation of GRF-Binding Sites*

1986 • 100 citations

Growth hormone responses to multiple injections of a fragment of human growth hormone-releasing factor in conscious male and female rats

1985 • 97 citations

Growth induced by pulsatile infusion of an amidated fragment of human growth hormone releasing factor in normal and GHRF-deficient rats

1985 • 95 citations

Inhibitory Effect of Hypothalamic Medial Preoptic Area Somatostatin on Growth Hormone-Releasing Factor in the Rat

1988 • 89 citations

REASONS FOR THE VARIABILITY IN GROWTH HORMONE (GH) RESPONSES TO GHRH CHALLENGE: THE ENDOGENOUS HYPOTHALAMIC‐SOMATOTROPH RHYTHM (HSR)

1989 • 78 citations

Withdrawal of endogenous somatostatin induces secretion of growth hormone-releasing factor in rats

1988 • 77 citations

Effect of Somatostatin Withdrawal and Growth Hormone (GH)-Releasing Factor on GH Releasein Vitro: Amount Available for Release after Disinhibition*

1986 • 74 citations

Stimulation of Somatostatin Releasein Vitroby Synthetic Human Growth Hormone-Releasing Factor by a Nondopaminergic Mechanism*

1985 • 65 citations

Somatostatin: A Physiological Role in the Regulation of Growth Hormone Secretion in the Adolescent Male Baboon*

1978 • 64 citations

Combined Effects of Human Growth Hormone (GH)-Releasing Factor-44 (GRF) and Somatostatin (SRIF) on Post-SRIF Rebound Release of GH and Prolactin: A Model for GRF-SRIF Modulation of Secretion*

1988 • 53 citations

Paradoxical Growth-Promoting Effects Induced by Patterned Infusions of Somatostatin in Female Rats*

1988 • 53 citations

Pulsatile, synchronous basal insulin and glucagon secretion in man

1982 • 52 citations

The Physiological Effects of Insulin-Induced Hypoglycaemia in Man: Responses at Differing Levels of Blood Glucose

1983 • 51 citations

Influence of Synthetic Somatostatin upon Growth Hormone Release from Perifused Rat Pituitaries

1976 • 49 citations

The Effect of Pulsatile Administration, Continuous Infusion, and Diurnal Variation on the Growth Hormone (GH) Response to GH-Releasing Hormone in Normal Men*

1986 • 48 citations

Physiological Role of Somatostatin-Mediated Autofeedback Regulation for Growth Hormone: Importance of Growth Hormone in Triggering Somatostatin Release during a Trough Period of Pulsatile Growth Hormone Release in Conscious Male Rats

1989 • 48 citations

The episodic secretory pattern of growth hormone regulates liver carbonic anhydrase III. Studies in normal and mutant growth-hormone-deficient dwarf rats

1990 • 46 citations

Post-somatostatin rebound secretion of growth hormone is dependent on growth hormone-releasing factor in unrestrained female rats

1989 • 40 citations

Characteristics of the Post-Somatostatin Rebound in Growth Hormone Secretion from Perifused Somatotrophs*

1983 • 39 citations

Periodic interactions of GH-releasing factor and somatostatin can augment GH release in vitro

1987 • 34 citations

Effect of Overnight Constant Infusion of Human Growth Hormone (GH)-Releasing Hormone-(1–44) on 24-Hour GH Secretion in Children with Partial GH Deficiency

1986 • 33 citations

Plasma Growth Hormone (GH) Response to Intravenous GH-Releasing Factor (GRF) in Adult Rats: Evidence for Transient Pituitary Desensitization after GRF Stimulation*

1987 • 28 citations

Pituitary Immediate Release Pools of Growth Hormone and Prolactin Are Preferentially Refilled by New Rather than Stored Hormone*

1989 • 24 citations

Somatostatin partially reverses desensitization of somatotrophs induced by growth hormone-releasing factor

1987 • 24 citations

Pulsatile Growth Hormone Secretion in Patients with Acromegaly and Normal Men: The Effects of Growth Hormone-Releasing Hormone Infusion

1990 • 23 citations

CONTINUOUS SUBCUTANEOUS GROWTH HORMONE RELEASING FACTOR ANALOGUE AUGMENTS GROWTH HORMONE SECRETION IN NORMAL MALE SUBJECTS WITH NO DESENSITIZATION OF THE SOMATOTROPH

1988 • 23 citations

CONTINUOUS SUBCUTANEOUS GHRH(1‐29)NH2 PROMOTES GROWTH OVER 1 YEAR IN SHORT, SLOWLY GROWING CHILDREN

1990 • 22 citations

Somatostatin prevents the desensitizing action of growth hormone-releasing factor on growth hormone release

1987 • 21 citations

INTERACTION BETWEEN GROWTH HORMONE RELEASING FACTOR (GRF) AND SOMATOSTATIN ANALOGUE (SMS 201–995) IN NORMAL SUBJECTS

1985 • 20 citations

Impaired Inhibitory Effects of Somatostatin on Growth Hormone (GH)-Releasing Hormone Stimulation of GH Secretion after Short Term Infusion*

1990 • 20 citations

Secretory bursts of growth hormone secretion in the dog may be initiated by somatostatin withdrawal

1984 • 19 citations

The pituitary gland is capable of responding to two successive doses of growth hormone releasing hormone (GHRH)

1991 • 16 citations

Effects of Somatostatin on the Growth Hormone‐Releasing Factor‐Induced Growth Hormone Secretion in Rats with Electrical and Chemical Inhibitions of Endogenous Growth Hormone‐Releasing Factor and Somatostatin

1990 • 13 citations

THE INTERACTION BETWEEN CLONIDINE AND GROWTH HORMONE RELEASING HORMONE IN THE STIMULATION OF GROWTH HORMONE SECRETION IN MAN

1990 • 11 citations

SUBCUTANEOUS GROWTH HORMONE‐RELEASING HORMONE AUGMENTS PULSATILE NOCTURNAL GH RELEASE IN GH‐INSUFFICIENT CHILDREN, BUT MAY ALSO RAISE BASAL GH SECRETION

1990 • 6 citations

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The interaction of growth hormone releasing hormone and somatostatin in the generation of… (1991) – Clinical Endocrinology | Metascience Observatory Explorer