Monoclonal Antibodies That Block the Activity of Leukocyte Function-associated Antigen 1 Recognize Three Discrete Epitopes in the Inserted Domain of CD11a

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

LEUKOCYTE ADHESION DEFICIENCY: An Inherited Defect in the Mac-1, LFA-1, and p150,95 Glycoproteins

1987 • 1,147 citations

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.

1989 • 1,115 citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

1988 • 967 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 962 citations

ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18).

1990 • 898 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 785 citations

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

1982 • 740 citations

Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies.

1983 • 674 citations

ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM

1988 • 631 citations

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1993 • 546 citations

The Leukocyte Integrins

1989 • 542 citations

Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion

1991 • 532 citations

Inherited deficiency of the Mac-1, LFA-1, p150,95 glycoprotein family and its molecular basis.

1984 • 495 citations

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.

1992 • 437 citations

A novel divalent cation-binding site in the a domain of the ?2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1993 • 383 citations

A human lymphocyte‐associated antigen involved in cell‐mediated lympholysis

1983 • 315 citations

Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.

1989 • 285 citations

The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunit. Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B.

1988 • 281 citations

The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor.

1988 • 279 citations

cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

1987 • 277 citations

Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule

1986 • 275 citations

The Role of the LFA‐1/ICAM‐1 Interaction in Human Leukocyte Homing and Adhesion

1989 • 254 citations

Deficiency of a leukocyte surface glycoprotein (LFA-1) in two patients with Mo1 deficiency. Effects of cell activation on Mo1/LFA-1 surface expression in normal and deficient leukocytes.

1984 • 224 citations

Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion.

1991 • 223 citations

A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/CD18).

1990 • 196 citations

Direct evidence for two affinity states for lymphocyte function-associated antigen 1 on activated T cells.

1993 • 195 citations

Two functional domains in the phagocyte membrane glycoprotein Mo1 identified with monoclonal antibodies.

1986 • 174 citations

Amino acid sequence of the murine Mac-1 alpha chain reveals homology with the integrin family and an additional domain related to von Willebrand factor.

1988 • 160 citations

The human lymphocyte function-associated (HLFA) antigen and a related macrophage differentiation antigen (HMac-1): functional effects of subunit-specific monoclonal antibodies.

1985 • 152 citations

Interaction of leukocyte integrins with ligand is necessary but not sufficient for function.

1992 • 151 citations

I domain of beta 2 integrin lymphocyte function-associated antigen-1 contains a binding site for ligand intercellular adhesion molecule-1.

1994 • 151 citations

Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1.

1981 • 126 citations

The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain.

1994 • 118 citations

On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules.

1990 • 107 citations

Role of the LFA-1 molecule in cellular interactions required for antibody production in humans.

1986 • 105 citations

Integrin LFA-1 alpha subunit contains an ICAM-1 binding site in domains V and VI.

1994 • 85 citations

Antigens involved in mouse cytolytic T-lymphocyte (CTL)-mediated killing: Functional screening and topographic relationship

1982 • 79 citations

Deficiency of the adhesive protein complex lymphocyte function antigen 1, complement receptor type 3, glycoprotein p150,95 in a girl with recurrent bacterial infections. Effects on phagocytic cells and lymphocyte functions.

1985 • 75 citations

Effects of monoclonal antibodies to the a and β chains of the human lymphocyte function‐associated (H‐LFA‐1) antigen on T lymphocyte functions

1985 • 53 citations

Structure and Regulation of the Leukocyte Adhesion Receptor LFA-1 and Its Counterreceptors, ICAM-1 and ICAM-2

1989 • 34 citations

Analysis of the role of leukocyte function-associated antigen-1 in activation of human influenza virus-specific T cell clones.

1990 • 18 citations

Biosynthesis and function of membrane bound and secreted forms of recombinant CD11b/CD18 (Mac‐1)

1993 • 14 citations

Immunochemistry of cytochrome c. Identification of antigenic determinants through the study of hybrid molecules.

1980 • 10 citations