Interaction of human PD-L1 and B7-1

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

2000 • 4,853 citations

PD-1 and Its Ligands in Tolerance and Immunity

2008 • 4,838 citations

Restoring function in exhausted CD8 T cells during chronic viral infection

2005 • 3,743 citations

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

2006 • 2,521 citations

Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses

2007 • 1,603 citations

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

2006 • 1,485 citations

Blockade of Programmed Death-1 Ligands on Dendritic Cells Enhances T Cell Activation and Cytokine Production

2003 • 933 citations

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

2006 • 859 citations

CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics

1997 • 525 citations

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

2001 • 459 citations

CD28- T lymphocytes. Antigenic and functional properties.

1993 • 403 citations

The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors

2008 • 402 citations

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1–PD-L1 pathway

2006 • 303 citations

Developmentally regulated expression of the PD-1 protein on the surface of double-negative(CD4^–CD8^–) thymocytes

1996 • 243 citations

Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy

2007 • 237 citations

PD-1 Regulates Self-Reactive CD8+ T Cell Responses to Antigen in Lymph Nodes and Tissues

2007 • 237 citations

Differential binding properties of B7-H1 and B7-DC to programmed death-1

2003 • 198 citations

Programmed Death-1 (PD-1):PD-Ligand 1 Interactions Inhibit TCR-Mediated Positive Selection of Thymocytes

2005 • 138 citations

Global Analysis of a Macromolecular Interaction Measured on BIAcore

1996 • 103 citations