A survey of furin substrate specificity using substrate phage display

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

1992 • 688 citations

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

1992 • 628 citations

The new enzymology of precursor processing endoproteases.

1992 • 608 citations

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1991 • 590 citations

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.

1994 • 494 citations

An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins.

1988 • 374 citations

Substrate Phage: Selection of Protease Substrates by Monovalent Phage Display

1993 • 337 citations

Selecting high-affinity binding proteins by monovalent phage display

1991 • 312 citations

Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

1990 • 259 citations

Affinity Maturation of Human Growth Hormone by Monovalent Phage Display

1993 • 227 citations

Structure and expression of mouse furin, a yeast Kex2-related protease. Lack of processing of coexpressed prorenin in GH4C1 cells.

1990 • 219 citations

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant.

1993 • 211 citations

Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

1990 • 202 citations

Purification and characterization of furin, a Kex2-like processing endoprotease, produced in Chinese hamster ovary cells.

1992 • 156 citations

Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage.

1992 • 154 citations

Transient production of proteins using an adenovirus transformed cell line

1990 • 129 citations

Processing of Protein Precursors by a Novel Family of Subtilisin-Related Mammalian Endoproteases

1993 • 97 citations

Arg15-Lys17-Arg18 turkey ovomucoid third domain inhibits human furin

1993 • 80 citations

Mammalian cell transient expression of tissue factor for the production of antigen

1990 • 50 citations

Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones.

1992 • 49 citations

Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones

1992 • 24 citations