Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

1989 • 2,127 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Carnitine--metabolism and functions

1983 • 1,620 citations

Purification of the human intestinal brush border membrane

1973 • 799 citations

Molecular and Functional Identification of Sodium Ion-dependent, High Affinity Human Carnitine Transporter OCTN2

1998 • 694 citations

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

1999 • 540 citations

An improved method for enzymic determination of glucose in the presence of maltose

1969 • 520 citations

Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells.

1985 • 497 citations

Cloning and characterization of a novel human pH‐dependent organic cation transporter, OCTN1

1997 • 454 citations

A one-step ultramicro method for the assay of intestinal disaccharidases

1966 • 420 citations

cDNA Sequence, Transport Function, and Genomic Organization of Human OCTN2, a New Member of the Organic Cation Transporter Family

1998 • 336 citations

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.

1999 • 328 citations

ORGANIC CATION TRANSPORTERS IN INTESTINE, KIDNEY, LIVER, AND BRAIN

1998 • 312 citations

Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.

1999 • 308 citations

Molecular and Functional Characterization of Organic Cation/Carnitine Transporter Family in Mice

2000 • 291 citations

Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.

1999 • 259 citations

Analytical isolation of plasma membranes of intestinal epithelial cells: Identification of Na, K-ATPase rich membranes and the distribution of enzyme activities

1976 • 241 citations

Transient mosaic patterns of morphological and functional differentiation in the Caco-2 cell line

1992 • 219 citations

Caco‐2 cells as a model for intestinal lipoprotein synthesis and secretion

1995 • 205 citations

Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

2000 • 196 citations

Common characteristics for Na+-dependent sugar transport in Caco-2 cells and human fetal colon

1987 • 194 citations

Primary and Secondary Carnitine Deficiency Syndromes

1995 • 192 citations

Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

2000 • 188 citations

Rapid Report

2001 • 187 citations

Molecular and Physiological Evidence for Multifunctionality of Carnitine/Organic Cation Transporter OCTN2

2001 • 183 citations

Genetic Epidemiology of the Carnitine Transporter OCTN2 Gene in a Japanese Population and Phenotypic Characterization in Japanese Pedigrees with Primary Systemic Carnitine Deficiency

1999 • 170 citations

Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2

1990 • 163 citations

Transport of bile acids in a human intestinal epithelial cell line, Caco-2

1990 • 136 citations

Carnitine Transport by Organic Cation Transporters and Systemic Carnitine Deficiency

2001 • 134 citations

The Role of Carnitine Supplementation during Valproic Acid Therapy

2000 • 123 citations

Cloning and functional characterization of a new subtype of the amino acid transport system N

2001 • 120 citations

Molecular Cloning and Characterization of High-Affinity Carnitine Transporter from Rat Intestine

1998 • 102 citations

Expression and localization of GLUT-5 in Caco-2 cells, human small intestine, and colon

1992 • 85 citations

Carnitine deficiency and hyperammonemia in children receiving valproic acid with and without other anticonvulsant drugs

1999 • 82 citations

H+-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics

1993 • 79 citations

Valproic Acid Impairs Carnitine Uptake in Cultured Human Skin Fibroblasts. An In Vitro Model for the Pathogenesis of Valproic Acid–Associated Carnitine Deficiency

1993 • 74 citations

Alkaline phosphatase in adaptation to low dietary phosphate intake.

1979 • 69 citations

Carnitine Transporter OCTN2 Mutations in Systemic Primary Carnitine Deficiency: A Novel Arg169Gln Mutation and a Recurrent Arg282ter Mutation Associated with an Unconventional Splicing Abnormality

1999 • 68 citations

Identification of two novel mutations in OCTN2 of three patients with systemic carnitine deficiency

1999 • 64 citations

Carnitine transport in human intestinal biopsy specimens

1986 • 55 citations

Carnitine transport in rat small intestine

1983 • 54 citations

In vivo studies of intestinal carnitine absorption in rats

1985 • 54 citations

Characterization of the Human Plasmalemmal Carnitine Transporter in Cultured Skin Fibroblasts

1996 • 49 citations

Studies on Intestinal Absorption of Sulpiride. (1): Carrier-Mediated Uptake of Sulpiride in the Human Intestinal Cell Line Caco-2.

2002 • 48 citations

Proline uptake by monolayers of human intestinal absorptive (Caco-2) cells in vitro

1992 • 47 citations

Studies on Intestinal Absorption of Sulpiride (2): Transepithelial Transport of Sulpiride Across the Human Intestinal Cell Line Caco-2.

2002 • 46 citations

Functional Characterization of Intestinal L-Carnitine Transport

2002 • 39 citations

Characterization of MPP⁺ secretion across human intestinal Caco‐2 cell monolayers: role of P‐glycoprotein and a novel Na⁺‐dependent organic cation transport mechanism

2000 • 31 citations

Uptake of l-carnitine, d-carnitine and acetyl-l-carnitine by isolated guinea-pig enterocytes

1986 • 29 citations

L-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles

2002 • 28 citations

Uptake of L-carnitine by a human intestinal epithelial cell line, Caco- 2

1996 • 28 citations

Family and Personal History

1995 • 27 citations

Uptake ofl-carnitine by rat jejunal brush border microvillous membrane vesicles

1990 • 26 citations

Characteristics of L-Carnitine Transport in Cultured Human Hepatoma HLF Cells

1999 • 23 citations

Reversal of Valproic Acid-Associated Impairment of Carnitine Uptake in Cultured Human Skin Fibroblasts

1994 • 18 citations

Evaluation of the Cytotoxicity of Sodium Valproate on Primary Cultured Rat Hepatocytes

1988 • 14 citations

Heterozygotes for plasmalemmal carnitine transporter defect are at increased risk for valproic acid‐associated impairment of carnitine uptake in cultured human skin fibroblasts

1994 • 11 citations

Carnitine transport in human intestinal biopsy specimens

1986 • 10 citations

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2000 • 8 citations