Genomic organization and chromosomal assignment for a serine protease gene (CSPB) expressed by human cytotoxic lymphocytes

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

THE MUTATION AND POLYMORPHISM OF THE HUMAN β-GLOBIN GENE AND ITS SURROUNDING DNA

1984 • 404 citations

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1987 • 393 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

1979 • 340 citations

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization.

1984 • 329 citations

Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides

1983 • 295 citations

Cloning of a cDNA for a T Cell-Specific Serine Protease from a Cytotoxic T Lymphocyte

1986 • 247 citations

Novel Serine Proteases Encoded by Two Cytotoxic T Lymphocyte-Specific Genes

1986 • 246 citations

Homologies in serine proteinases

1970 • 239 citations

Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes.

1987 • 236 citations

Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.

1986 • 222 citations

Split-gene evolution: Exon shuffling and intron insertion in serine protease genes

1985 • 217 citations

The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14

1986 • 197 citations

The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer.

1988 • 181 citations

Structure of two related rat pancreatic trypsin genes.

1984 • 177 citations

Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin

1987 • 158 citations

The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases.

1980 • 155 citations

An Improved strategy for rapid direct sequencing of both strands of long DNA molecules cloned in a plasmid

1983 • 153 citations

Cell-specific enhancers in the rat exocrine pancreas.

1986 • 150 citations

Inhibition of human natural cytotoxicity by macromolecular antiproteases.

1981 • 147 citations

Interleukin 2 (IL2) is assigned to human chromosome 4

1984 • 143 citations

A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor.

1988 • 130 citations

Isolation and sequence of a rat chymotrypsin B gene.

1984 • 128 citations

Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family.

1987 • 122 citations

Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease.

1988 • 118 citations

Assignment of the β-glucuronidase structural gene to the pter→q22 region of chromosome 7 in man

1978 • 117 citations

Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes.

1986 • 112 citations

Effects of N alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes.

1980 • 105 citations

The Isolation and Characterization of a Family of Serine Protease Genes Expressed in Activated Cytotoxic T Lymphocytes

1988 • 95 citations

Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway.

1988 • 92 citations

Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes.

1988 • 92 citations

Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes.

1988 • 91 citations

The nucleotide sequence of three genes participating in the adipose differentiation of 3T3 cells.

1986 • 89 citations

Functional channel formation associated with cytotoxic T-cell granules.

1986 • 78 citations

The requirement for proteinase activity for human lymphocyte-mediated natural cytotoxicity (NK): evidence that the proteinase is serine dependent and has aromatic amino acid specificity of cleavage.

1984 • 72 citations

Extracellular release of lymphocyte cytolytic pore-forming protein (perforin) after ionophore stimulation.

1986 • 61 citations

cDNA cloning of granzyme C, a granule-associated serine protease of cytolytic T lymphocytes.

1988 • 57 citations

The mechanism of human NK cell-mediated cytotoxicity. Mode of action of surface-associated proteases in the early stages of the lytic reaction.

1985 • 45 citations

A serine protease (CCP1) is sequestered in the cytoplasmic granules of cytotoxic T lymphocytes.

1987 • 41 citations

Proximity of the CTLA-1 serine esterase and Tcr ? loci in mouse and man

1988 • 39 citations

Role of granule proteins in lymphocyte‐mediated killing

1986 • 37 citations

Amino acid sequences of transport peptides associated with canine exocrine pancreatic proteins.

1982 • 36 citations

Activatable esterase activity of murine natural killer cell-yac tumour cell conjugates

1984 • 29 citations

Deleted Work

1955 • 0 citations