Activation of Adenylyl Cyclase by Preincubation of Rat Cerebral‐Cortical Membranes Under Phosphorylating Conditions: Role of ATP, GTP, and Divalent Cations

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylate

1979 • 1,976 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

1979 • 1,648 citations

Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor

1982 • 1,138 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Phosphorylated Proteins as Physiological Effectors

1978 • 975 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

The enzymatic preparation of [α-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMP

1979 • 574 citations

Progress in Brain Research, vol 16.

1966 • 496 citations

Adenosine 3':5'-monophosphate-regulated phosphoprotein system of neuronal membranes. I. Solubilization, purification, and some properties of an endogenous phosphoprotein.

1977 • 411 citations

Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein

1978 • 332 citations

Activation and attenuation of adenylate cyclase. The role of GTP-binding proteins as macromolecular messengers in receptor–cyclase coupling

1981 • 322 citations

Roles of calcium and phosphorylation in the regulation of the activity of gizzard myosin

1978 • 244 citations

Irreversible thiophosphorylation and activation of tension in functionally skinned rabbit ileum strips by [35S]ATP gamma S.

1979 • 181 citations

Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation

1980 • 178 citations

Calcium-dependent adenylate cyclase from rat cerebral cortex. Reversible activation by sodium fluoride.

1977 • 176 citations

Cholera toxin activation of adenylate cyclase. Roles of nucleoside triphosphates and a macromolecular factor in the ADP ribosylation of the GTP-dependent regulatory component.

1980 • 148 citations

Benzodiazepine Inhibition of the Calcium-Calmodulin Protein Kinase System in Brain Membrane

1981 • 115 citations

Turnover of protein-bound phosphorylserine in membrane preparations from ox brain catalysed by intrinsic kinase and phosphatase activity

1971 • 108 citations

The enzymatic preparation of [γ-^ P] nucleotide triphosphate, cyclic [^ P] AMP, and cyclic GMP

1979 • 106 citations

Activation of Turkey erythrocyte adenylate cyclase and blocking of the catecholamine-stimulated GTPase by guanosine 5′-(γ-thio) triphosphate

1977 • 106 citations

Calcium‐Stimulated Adenosine Triphosphatases in Synaptic Membranes

1981 • 105 citations

Protein kinase activity in membrane preparations from ox brain. Stimulation of intrinsic activity by adenosine 3′:5′-cyclic monophosphate

1973 • 93 citations

Endogenous phosphorylation of four cerebral cortical membrane proteins: Role of cyclic nucleotides, ATP and divalent cations

1975 • 86 citations

Calcium-dependent phosphorylation of specific synaptosomal fraction proteins: Possible role of phosphoproteins in mediating neurotransmitter release

1976 • 82 citations

Evidence for specific binding sites for guanine nucleotides in adipocyte and hepatocyte plasma membranes. A difference in fate of GTP and guanosine 5'-(beta, gamma-imino) triphosphate.

1975 • 79 citations

Cyclic AMP regulates phosphorylation of three protein components of rat cerebral cortex membranes for thirty minutes

1974 • 75 citations

Mechanism of desensitization of adenylate cyclase in lutropin. GTP-dependent uncoupling of the receptor.

1980 • 74 citations

Phosphorylation and dephosphorylation of membrane proteins as a possible mechanism for structural rearrangement of membrane components

1976 • 72 citations

The activation of adenylate cyclase: II. The postulated presence of (A) adenylate cyclase in a phospho (inhibited) form (B) a dephospho (activated) form with a cyclic adenylate stimulated membrane protein kinase

1973 • 71 citations

Divalent cation-induced desensitization of glucagon-stimulable adenylyl cyclase in rat liver plasma membrane. GTP-dependent stimulation by glucagon.

1980 • 64 citations

Protein Kinases and Phosphatases

1983 • 60 citations

Guanyl nucleotide regulation of hormonally-responsive adenylyl cyclases

1979 • 59 citations

Mechanism of desensitization of adenylate cyclase by lutropin. Impaired introduction of GTP into the regulatory site.

1981 • 56 citations

Interaction of soluble brain adenylate cyclase with manganese.

1979 • 53 citations

Isoproterenol-induced desensitization of adenylate cyclase responsiveness in a cell-free system.

1979 • 52 citations

Increase in the size of soluble brain adenylate cyclase with activation by guanosine 5'-(beta, gamma-imino)triphosphate.

1980 • 48 citations

Demonstration of the heterogeneity of nucleoside diphosphokinase in rat tissues

1973 • 43 citations

Transient Changes in the Phosphorylation of Cortical Membrane Proteins After Electroconvulsive Shock

1980 • 42 citations

Resensitization of the Desensitized Follicular Adenylyl Cyclase System to Luteinizing Hormone*

1979 • 41 citations

The Behaviorally Active Neuropeptide ACTH as Neurohormone and Neuromodulator: The Role of Cyclic Nucleotides and Membrane Phosphoproteins

1979 • 41 citations

Modulators, Mediators, and Specifiers in Brain Function

1979 • 38 citations

beta-Adrenergic receptor regulation by agonists and membrane depolarization in rat brain slices.

1979 • 33 citations

Partial purification and characterization of a macromolecule which enhances fluoride activation of adenylate cyclase.

1980 • 27 citations

ATP-dependent activation of adenylate cyclase.

1981 • 25 citations

Observations on the Phosphotungstates of certain Bases and Amino-acids

1918 • 24 citations

Induction of Cholinergic Expression in Developing Spinal Cord Cultures

1983 • 23 citations

Phosphoproteins as Specifiers for Mediators and Modulators in Neuronal Function

1979 • 23 citations

Calcium-Stimulated Protein Phosphorylation in Synaptic Membranes

1983 • 21 citations

Long duration phosphorylation of synaptic membrane proteins

1979 • 20 citations

Endorphin-regulated protein phosphorylation in brain membranes

1980 • 17 citations

A high-spatial-resolution laser beam densitometer for quantitative analysis of polyacrylamide gels

1983 • 10 citations

Protein phosphorylation mediates effects of isoproterenol on adenylate cyclase activity in rat cortical membranes

1981 • 9 citations

GTP-preferring protein phosphorylation systems in brain membranes: Possible role in adenylate cyclase regulation

1982 • 9 citations

Advances in cyclic nucleotide research, vol. 10, current methodology

1979 • 4 citations