Functional Inactivation in the Whole Population of Human Vγ9/Vδ2 T Lymphocytes Induced By a Nonpeptidic Antagonist

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

1987 • 1,166 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Altered Peptide Ligand–Induced Partial T Cell Activation: Molecular Mechanisms and Role in T Cell Biology

1996 • 698 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Partial T cell signaling: Altered phospho-? and lack of zap70 recruitment in APL-induced T cell anergy

1994 • 608 citations

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

1993 • 595 citations

Isolation of CD4-CD8-mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid

1989 • 543 citations

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

ζ Phosphorylation Without ZAP-70 Activation Induced by TCR Antagonists or Partial Agonists

1995 • 510 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4 ⁺ T Cells

1996 • 438 citations

Blocked Ras Activation in Anergic CD4 ⁺ T Cells

1996 • 380 citations

Nonpeptide ligands for human gamma delta T cells.

1994 • 373 citations

Recognition by Human V _γ 9/V _δ 2 T Cells of a GroEL Homolog on Daudi Burkitt's Lymphoma Cells

1990 • 357 citations

Essential flexibility in the T-cell recognition of antigen

1996 • 330 citations

T cell receptor antagonists and partial agonists

1995 • 303 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.

1988 • 260 citations

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

1995 • 245 citations

Primary responses of human T cells to mycobacteria: a frequent set of γ/δ T cells are stimulated by protease‐resistant ligands

1990 • 243 citations

Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria.

1992 • 238 citations

Specificity and flexibility in thymic selection

1994 • 221 citations

Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells.

1991 • 201 citations

Split Anergy in a CD8 ⁺ T Cell: Receptor-dependent Cytolysis in the Absence of Interleukin-2 Production

1991 • 199 citations

Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands.

1995 • 177 citations

Frontiers of the immune system

1988 • 174 citations

Functional consequences of engagement of the T cell receptor by low affinity ligands.

1993 • 171 citations

Human Vγ9‐Vδ2 cells are stimulated in a crossreactive fashion by a variety of phosphorylated metabolites

1995 • 168 citations

Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria.

1990 • 167 citations

Predominant activation and expansion of V gamma 9-bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection.

1992 • 154 citations

Transient increase in circulating gamma/delta T cells during Plasmodium vivax malarial paroxysms.

1994 • 114 citations

Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor.

1994 • 102 citations

Polyclonal expansion of peripheral gamma delta T cells in human Plasmodium falciparum malaria

1994 • 92 citations

Endogenous altered peptide ligands can affect peripheral T cell responses.

1996 • 59 citations

Autologous rat myelin basic protein is a partial agonist that is converted into a full antagonist upon blockade of CD4. Evidence for the integration of efficacious and nonefficacious signals during T cell antigen recognition.

1995 • 55 citations

The T cell receptor as a diverse signal transduction machine.

1996 • 22 citations