PHYSIOLOGICAL IMPLICATIONS OF STEROL BIOSYNTHESIS IN YEAST

Terbinafine: Mode of action and properties of the squalene epoxidase inhibition

1992 • 408 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol.

1989 • 259 citations

Metabolism of Sterols in Yeast

1978 • 187 citations

Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.

1993 • 154 citations

Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase

1991 • 152 citations

Biosynthesis of ergosterol in yeast. Evidence for multiple pathways

1973 • 122 citations

8 Regulation and Compartmentalization of Lipid Synthesis in Yeast

1992 • 121 citations

Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast sterol auxotrophs

1983 • 110 citations

The Structural Requirements of Sterols for Membrane Function in Saccharomyces cerevisiae

1993 • 101 citations

Location and regulation of early enzymes of sterol biosynthesis in yeast

1976 • 73 citations

Involvement of heme biosynthesis in control of sterol uptake by Saccharomyces cerevisiae

1985 • 68 citations

Brefeldin A causes a defect in secretion in Saccharomyces cerevisiae.

1993 • 61 citations

ESR determination of membrane order parameter in yeast sterol mutants

1979 • 58 citations

Isolation of pleiotropic yeast mutants requiring ergosterol for growth

1973 • 55 citations

Regulation of squalene synthetase and squalene epoxidase activities insaccharomyces cerevisiae

1989 • 52 citations

<scp>XIII</scp>. Yeast sequencing reports. SED6 is identical to ERG6, and encodes a putative methyltransferase required for ergosterol synthesis

1994 • 45 citations

On the role of the sterol hydroxyl group in membranes.

1979 • 43 citations

Sterol metabolism of micro-organisms

1940 • 40 citations

Enhancement by tamoxifen of the membrane antioxidant action of the yeast membrane sterol ergosterol: relevance to the antiyeast and anticancer action of tamoxifen

1993 • 38 citations

Comparative responses of the yeast mutant strain GL7 to lanosterol, cycloartenol, and cyclolaudenol

1980 • 37 citations

Role of sterol structure in the thermotropic behavior of plasma membranes of Saccharomyces cerevisiae

1983 • 36 citations

Neutral lipids in the cells and cell envelope fractions of aerobic baker's yeast and anaerobic brewer's yeast

1975 • 36 citations

Stimulation by heme of steryl ester synthase and aerobic sterol exclusion in the yeast Saccharomyces cerevisiae

1992 • 23 citations

Modulation of yeast plasma membrane composition of a yeast sterol auxotroph as a function of exogenous sterol

1985 • 22 citations

Effect of 5,7‐unsaturated sterols on ethanol tolerance in Saccharomyces cerevisiae.“

1992 • 22 citations

Inhibition of sterol synthesis by delta 5-sterols in a sterol auxotroph of yeast defective in oxidosqualene cyclase and cytochrome P-450.

1988 • 18 citations

Effect of sterol alterations on conjugation in Saccharomyces cerevisiae

1992 • 17 citations

Accumulation of a sterol intermediate during reaction in the presence of homocysteine with cell-free extract of yeast

1974 • 15 citations

Biosynthesis of Ergosterol in Cell-Free System of Yeast&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;&lt;xref ref-type="fn" rid="fn2"&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/xref&gt;

1980 • 12 citations

Phospholipid synthesis inS. cerevisiae strain GL7 grown without unsaturated fatty acid supplements

1982 • 8 citations

Regulation of squalene epoxidase activity by membrane fatty acid composition in yeast

1988 • 8 citations