Inhibition of sterol synthesis by delta 5-sterols in a sterol auxotroph of yeast defective in oxidosqualene cyclase and cytochrome P-450.

Biochemistry of steroids and other isopentenoids

1977 • 489 citations

The Metabolism, Structure, and Function of Plant Lipids

1987 • 263 citations

Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

1986 • 231 citations

Yeast mutants deficient in heme biosynthesis and a heme mutant additionally blocked in cyclization of 2,3-oxidosqualene.

1977 • 231 citations

Studies on the biosynthesis of cholesterol. III. Purification of C14-cholesterol from perfusions of livers and other organs

1952 • 199 citations

The functional importance of structural features of ergosterol in yeast.

1978 • 160 citations

Sterol Biosynthesis

1982 • 143 citations

Ecology and Metabolism of Plant Lipids

1987 • 138 citations

A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: positive in vivo regulation by sterol.

1987 • 124 citations

The phylogenetic distribution of sterols in tracheophytes

1977 • 117 citations

Regulation of early enzymes of ergosterol biosynthesis in Saccharomyces cerevisiae

1986 • 111 citations

Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast sterol auxotrophs

1983 • 110 citations

A requirement for ergosterol to permit growth of yeast sterol auxotrophs on cholestanol

1982 • 102 citations

The stereospecificity of carbanion reduction processes

1954 • 97 citations

Cytochrome P-450-dependent oxidation of lanosterol in cholesterol biosynthesis. Microsomal electron transport and C-32 demethylation.

1984 • 95 citations

The 14α—demethylation of lanosterol by a reconstituted cytochrome P-450 system from yeast microsomes

1978 • 91 citations

Sterols in membranes: growth characteristics and membrane properties of Mycoplasma capricolum cultured on cholesterol and lanosterol

1980 • 90 citations

Sterol synergism in yeast.

1983 • 90 citations

Stereochemical specificity for sterols in Saccharomyces cerevisiae.

1983 • 83 citations

Studies on the biosynthesis of cholesterol. 4. Degradation of rings C and D

1957 • 76 citations

Sterols of the cucurbitaceae

1987 • 69 citations

Sterol methylation in Saccharomyces cerevisiae

1984 • 65 citations

Involvement of cytochrome P-450 in Δ22-desaturation in ergosterol biosynthesis of yeast

1981 • 62 citations

Studies on the mechanism of lanosterol 14 α-demethylation. A requirement for two distinct types of mixed-function-oxidase systems

1979 • 61 citations

Stereochemically distinct roles for sterol in Saccharomycescerevisiae

1983 • 56 citations

Microsomal enzymes of cholesterol biosynthesis from lanosterol. Solubilization and purification of steroid 8-isomerase.

1986 • 56 citations

Physiological requirement for biosynthesis of multiple 24β-methyl sterols in Gibberella fujikuroi

1986 • 53 citations

The Effects of Catabolite Derepression on the Accumulation of Steryl Esters and the Activity of -Hydroxymethylglutaryl-CoA Reductase in Saccharomyces cerevisiae

1979 • 47 citations

Control of fungal sterol C-24 transalkylation: Importance to developmental regulation

1986 • 47 citations

Occurrence of Δ5-sterols in plants producing predominantly Δ7-sterols: Studies on the sterol compositions of six cucurbitaceae seeds

1986 • 45 citations

Control of Ergosterol Biosynthesis in Yeast*

1970 • 43 citations

Sterol Biosynthesis in Yeast

1975 • 41 citations

Genetic and Biochemical Aspects of Yeast Sterol Regulation Involving 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

1981 • 39 citations

LM cell growth and membrane lipid adaptation to sterol structure.

1986 • 34 citations

Biosynthesis of isoprenoid compounds vol. 1

1983 • 33 citations

[1] A comparison of methods for the identification of sterols

1985 • 31 citations

Biosynthesis of ergosta-6(7),8(14),22(23)-trien-3β-ol by Gibberella fujikuroi: its importance to Ergosterol's metabolic pathway

1985 • 29 citations

Mevalonate synthesis in the mitochondria of yeast

1973 • 28 citations

Paclobutrazol inhibition of sterol biosynthesis in a cell suspension culture and evidence of an essential role for 24-ethylsterol in plant cell division

1987 • 28 citations

The effects of branching, oxygen, and chain length in the side chain of sterols on their metabolism by Tetrahymena pyriformis.

1980 • 26 citations

Inhibition of sterol biosynthesis by ergosterol and cholesterol in Saccharomyces cerevisiae

1985 • 25 citations

Inhibition of hepatic cholesterol synthesis in mice by sterols with shortened and stereochemically varied side chains.

1982 • 20 citations

Discrimination between cholesterol and ergosterol by yeast membranes

1976 • 19 citations

Growth support and metabolism of phytosterols inParamecium tetraurelia

1987 • 18 citations

Sterol uptake in the yeast, Saccharomyces cerevisiae

1983 • 17 citations

Evidence for facilitated transport in the absorption of sterols bySaccharomyces cerevisiae

1986 • 16 citations

Studies on Δ8–Δ7 Isomerization and Methyl Transfer of Sterols in Ergosterol Biosynthesis of Yeast1

1979 • 16 citations

Growth of a yeast mutant on ring a modified cholesterol derivatives

1982 • 12 citations

The isolation of two mutants of Saccharomycescerevisiae which demonstrate increased activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase

1980 • 11 citations

Stereochemistry of the palladium catalyzed exchange of deuterium with allylic hydrogens*1

1976 • 9 citations

Metabolism of sterols by anaerobicSaccharomyces cerevisiae

1981 • 7 citations