MHC heterozygosity confers a selective advantage against multiple-strain infections

Escherichia coli and Salmonella :cellular and molecular biology

1996 • 8,124 citations

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines

1981 • 2,042 citations

Common West African HLA antigens are associated with protection from severe malaria

1991 • 1,570 citations

HLA and HIV-1: Heterozygote Advantage and B*35 - Cw*04 Disadvantage

1999 • 1,229 citations

The Evolution of Mating Preferences and Major Histocompatibility Complex Genes

1999 • 764 citations

Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex

1975 • 751 citations

Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci.

1990 • 688 citations

The Scent of Genetic Compatibility: Sexual Selection and the Major Histocompatibility Complex

2002 • 517 citations

The Nature of Selection on the Major Histocompatibility Complex

2017 • 515 citations

Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population (Ovis aries L.)

1998 • 486 citations

Female sticklebacks count alleles in a strategy of sexual selection explaining MHC polymorphism

2001 • 472 citations

Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location.

1996 • 397 citations

Association between major histocompatibility complex class IIB alleles and resistance toAeromonas salmonicidain Atlantic salmon

2001 • 282 citations

‘Heads I win, tails you lose’: testing directional alternative hypotheses in ecological and evolutionary research

1994 • 247 citations

Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on listeria monocytogenes infection

1995 • 244 citations

Male-male competition magnifies inbreeding depression in wild house mice

2000 • 238 citations

Characterization of CD4+ T Cell Responses During Natural Infection with Salmonella typhimurium

2000 • 235 citations

Male–male competition magnifies inbreeding depression in wild house mice

2000 • 234 citations

The Influence of HLA Class I Alleles and Heterozygosity on the Outcome of Human T Cell Lymphotropic Virus Type I Infection

2000 • 217 citations

HETEROSIS AS AN EXPLANATION FOR LARGE AMOUNTS OF GENIC POLYMORPHISM

1978 • 205 citations

Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection.

1994 • 201 citations

Balancing selection and MHC.

1998 • 194 citations

T Cell Responses to Gram-Negative Intracellular Bacterial Pathogens: A Role for CD8+ T Cells in Immunity toSalmonellaInfection and the Involvement of MHC Class Ib Molecules

1999 • 169 citations

MAJOR-HISTOCOMPATIBILITY-COMPLEX-ASSOCIATED VARIATION IN SECONDARY SEXUAL TRAITS OF WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS): EVIDENCE FOR GOOD-GENES ADVERTISEMENT

2001 • 167 citations

Natural Resistance to Salmonellae in Mice: Control by Genes Within the Major Histocompatibility Complex

1985 • 88 citations

Increased reproductive success of MHC class II heterozygous males among free-ranging rhesus macaques

2001 • 88 citations

Female choice and variation in the major histocompatibility complex.

1992 • 86 citations

Structural diversity of the classical H-2 genes: K, D, and L.

1992 • 83 citations

MHC Class Ib-Restricted CTL Provide Protection Against Primary and SecondaryListeria monocytogenesInfection

2000 • 81 citations

Amplification of major histocompatibility complex class II gene diversity by intraexonic recombination.

1991 • 71 citations

How pure are inbred strains of mice?

1982 • 70 citations

Ancestral Polymorphism of Mhc Class II Genes in Mice: Implications for Balancing Selection and the Mammalian Molecular Clock

1997 • 67 citations

DistinctH-2complex control of mortality, and immune responses to tuberculosis infection in virgin and BCG-vaccinated mice

1993 • 63 citations

Role of H-2 and non-H-2 genes in control of bacterial clearance from the spleen in Salmonella typhimurium-infected mice

1988 • 56 citations

Linkage of Exogenous T-cell Epitopes to the 19-Kilodalton Region ofPlasmodium yoeliiMerozoite Surface Protein 1 (MSP1₁₉) Can Enhance Protective Immunity against Malaria and Modulate the Immunoglobulin Subclass Response to MSP1₁₉

2000 • 45 citations

Molecular mapping of murine I region recombinants: crossing over in the E beta gene.

1986 • 35 citations

MHC Polymorphism Can Enrich the T Cell Repertoire of the Species by Shifts in Intrathymic Selection

2000 • 34 citations

Mechanisms of protective immunity against 5. mansoni infection in mice vaccinated with irradiated cercariae. VI. Influence of the major histocompatibility complex

1984 • 33 citations

Genetic control of antibody responses induced against an antigen delivered by recombinant attenuated Salmonella typhimurium

1994 • 32 citations

Salmonella typhimurium virulence genes necessary to exploit the Itys/s genotype of the mouse

1986 • 30 citations

Dissemination and proliferation of Salmonella typhimurium in genetically resistant and susceptible mice

1992 • 25 citations

Major histocompatibility complex class I- and II-deficient knock-out mice are resistant to primary but susceptible to secondary Eimeria papillata infections

1998 • 14 citations

Control by H-2 genes of the Th1 response induced against a foreign antigen expressed by attenuated Salmonella typhimurium

1996 • 13 citations

Life-span, T-cell responses, and incidence of lymphomas in congenic mice.

1995 • 13 citations

An analysis of genetic factors regulating life-span in congeneic mice

1982 • 10 citations

Expression and immune response to foreign epitopes in bacteria. Perspectives for live vaccine development.

1997 • 9 citations

Deleted Work

1955 • 0 citations