Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence.

1988 • 604 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

Splice Junctions: Association with Variation in Protein Structure

1983 • 261 citations

Structure of a complex between yeast hexokinase A and glucose

1980 • 233 citations

The Amino Acid Sequence of Rat Liver Glucokinase Deduced from Cloned cDNA

1989 • 158 citations

The cAMP-binding domains of the regulatory subunit of cAMP-dependent protein kinase and the catabolite gene activator protein are homologous.

1982 • 132 citations

An intact hydrophobic N-terminal sequence is critical for binding of rat brain hexokinase to mitochondria

1985 • 131 citations

Sequencing a protein by X-ray crystallography

1978 • 131 citations

A refined model of the sugar binding site of yeast hexokinase B

1978 • 130 citations

Purification and Properties of Pig‐Heart Hexokinase

1973 • 115 citations

Human hexokinase: Sequences of amino- and carboxyl-terminal halves are homologous

1988 • 100 citations

The comparative isozymology of vertebrate hexokinases

1982 • 90 citations

Complete nucleotide sequence of the hexokinase PI gene (HXK1) of Saccharomyces cerevisiae

1985 • 83 citations

Rat brain hexokinase: The hydrophobie N-terminus of the mitochondrially bound enzyme is inserted in the lipid bilayer

1988 • 83 citations

Purification and properties of rat skeletal muscle hexokinase

1976 • 76 citations

Specificity for the glucose-6-P inhibition site of hexokinase

1974 • 71 citations

Identification, cloning and sequence determination of the genes specifying hexokinase A and B from yeast

1986 • 69 citations

Regulation of Carbohydrate Metabolism(1985)

2018 • 66 citations

Independent mutations at the amino terminus of a protein act as surrogate signals for mitochondrial import.

1987 • 59 citations

Rat brain hexokinase: Location of the allosteric regulatory site in a structural domain at the N-terminus of the enzyme

1987 • 56 citations

The complete amino acid sequence of the catalytic domain of rat brain hexokinase, deduced from the cloned cDNA.

1988 • 48 citations

An examination of the expected degree of sequence similarity that might arise in proteins that have converged to similar conformational states

1981 • 47 citations

Rat brain hexokinase: Location of the substrate nucleotide binding site in a structural domain at the C-terminus of the enzyme

1986 • 45 citations

Isotope‐Exchange Evidence that Glucose 6‐Phosphate Inhibits Rat‐Muscle Hexokinase II at an Allosteric Site

1983 • 36 citations

Proteolytic dissection of rat brain hexokinase: Determination of the cleavage pattern during limited digestion with trypsin

1984 • 35 citations

Rat brain hexokinase: Amino acid sequence at the substrate hexose binding site is homologous to that of yeast hexokinase

1987 • 30 citations

The 6-hydroxymethyl group of a hexose is essential for the substrateinduced closure of the cleft in hexokinase

1982 • 30 citations

Mutations restoring import of a yeast mitochondrial protein with a nonfunctional presequence.

1988 • 24 citations

A method for determining the intracellular distribution of enzymes in yeast provides no evidence for the association of hexokinase with mitochondria

1986 • 20 citations

Amino acid sequence homology between yeast hexokinases and rat hexokinase C

1986 • 14 citations

In vitro synthesis of rat brain hexokinase

1985 • 6 citations

Molecular symmetry and metastable states of enzymes exhibiting half-of-the-sites reactivity

1981 • 5 citations