Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion

Myeloid-derived suppressor cells as regulators of the immune system

2009 • 6,165 citations

M-1/M-2 Macrophages and the Th1/Th2 Paradigm

2000 • 2,865 citations

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation.

1992 • 1,849 citations

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

2006 • 1,366 citations

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

2009 • 1,341 citations

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors

2005 • 1,266 citations

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity

2008 • 1,185 citations

Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses

2004 • 1,136 citations

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

2010 • 1,128 citations

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells

2003 • 557 citations

IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

2003 • 499 citations

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer

2007 • 479 citations

Targeting the ANGPT–TIE2 pathway in malignancy

2010 • 426 citations

New vistas on macrophage differentiation and activation

2006 • 418 citations

Tumor-associated macrophages: Effectors of angiogenesis and tumor progression

2009 • 345 citations

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood “resident” monocytes, and embryonic macrophages suggests common functions and developmental relationships

2009 • 323 citations

Angiopoietin-2 Regulates Gene Expression in TIE2-Expressing Monocytes and Augments Their Inherent Proangiogenic Functions

2010 • 319 citations

Expression of Tie-2 by Human Monocytes and Their Responses to Angiopoietin-2

2007 • 311 citations

The p38 Mitogen-activated Kinase Pathway Regulates the Human Interleukin-10 Promoter via the Activation of Sp1 Transcription Factor in Lipopolysaccharide-stimulated Human Macrophages

2001 • 310 citations

Cutting Edge: Induction of B7-H4 on APCs through IL-10: Novel Suppressive Mode for Regulatory T Cells

2006 • 277 citations

Adenosine Augments IL-10 Production by Macrophages through an A2B Receptor-Mediated Posttranscriptional Mechanism

2005 • 262 citations

IL-10 Gene Expression Is Controlled by the Transcription Factors Sp1 and Sp3

2000 • 258 citations

Angiopoietin‐2 expression in breast cancer correlates with lymph node invasion and short survival

2002 • 200 citations

Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a

2009 • 196 citations

Host-Derived Angiopoietin-2 Affects Early Stages of Tumor Development and Vessel Maturation but Is Dispensable for Later Stages of Tumor Growth

2009 • 177 citations

Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors

2009 • 170 citations

Angiopoietin-2 Impairs Revascularization After Limb Ischemia

2007 • 105 citations

Characterization and Expression of a Novel Alternatively Spliced Human Angiopoietin-2

2000 • 66 citations

Angiopoietin 2 expression in invasive ductal carcinoma of the breast: its relationship to the VEGF expression and microvessel density

2006 • 57 citations

Chronic systemic delivery of angiopoietin-2 reveals a possible independent angiogenic effect

2006 • 24 citations