Trials and tribulations in the search for genes causing neuropsychiatric disorders

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Identification of the Cystic Fibrosis Gene: Genetic Analysis

1989 • 4,105 citations

Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping

1989 • 3,180 citations

A polymorphic DNA marker genetically linked to Huntington's disease

1983 • 2,329 citations

Instability of a 550-Base Pair DNA Segment and Abnormal Methylation in Fragile X Syndrome

1991 • 1,482 citations

Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients

1990 • 1,471 citations

Linkage strategies for genetically complex traits. I. Multilocus models.

1990 • 1,335 citations

Bipolar affective disorders linked to DNA markers on chromosome 11

1987 • 826 citations

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

1978 • 804 citations

Fragile X Genotype Characterized by an Unstable Region of DNA

1991 • 794 citations

Localization of a susceptibility locus for schizophrenia on chromosome 5

1988 • 624 citations

The Inheritance of Gilles de la Tourette's Syndrome and Associated Behaviors

1986 • 504 citations

Cystic Fibrosis Locus Defined by a Genetically Linked Polymorphic DNA Marker

1985 • 488 citations

Cloning of the cDNA and gene for a human D2 dopamine receptor.

1989 • 488 citations

Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region.

1989 • 479 citations

Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the Old Order Amish

1989 • 443 citations

A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10

1987 • 440 citations

The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.

1989 • 423 citations

Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage

1987 • 423 citations

Drift, admixture, and selection in human evolution: a study with DNA polymorphisms.

1991 • 413 citations

Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree

1988 • 394 citations

Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene

1987 • 379 citations

Report of the DNA committee and catalogs of cloned and mapped genes and DNA polymorphisms pp. 622-643

1989 • 212 citations

High-resolution analysis of a hypervariable region in the human apolipoprotein B gene.

1989 • 182 citations

Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene

1991 • 178 citations

Haplotype of multiple polymorphisms resolved by enzymatic amplification of single DNA molecules.

1990 • 151 citations

No Linkage Between D2 Dopamine Receptor Gene Region and Schizophrenia

1991 • 121 citations

Familial Tourette's syndrome

1986 • 110 citations

Studies of three Amerindian populations using nuclear DNA polymorphisms.

1991 • 103 citations

Mapping the Human Genome: Current Status

1990 • 88 citations

Report of the Committee on Human Gene Mapping by Recombinant DNA Techniques (Part 1 of 5)

1985 • 86 citations

Gilles de la Tourette Syndrome Is Not Linked to D2-Dopamine Receptor

1990 • 76 citations

Study of 47 DNA markers in five populations from four continents.

1987 • 64 citations

Human tyrosine hydroxylase and insulin genes are contiguous on chromosome 11.

1988 • 62 citations

Report of the DNA committee and catalogues of cloned and mapped genes and DNA polymorphisms (Part 1 of 14)

1990 • 54 citations

Report of the Committee on Human Gene Mapping by Recombinant DNA techniques (Part 1 of 9)

1987 • 52 citations

PCR analysis of DNA sequences in single cells: Single sperm gene mapping and genetic disease diagnosis

1990 • 49 citations

Multiple Human Tyrosine Hydroxylase Enzymes, Generated Through Alternative Splicing, Have Different Specific Activities in Xenopus Oocytes

1988 • 37 citations

The 1990 catalog of mapped genes and report of the nomenclature committee (Part 1 of 3)

1990 • 34 citations

Status of the search for a major genetic locus for affective disorder in the Old Order Amish

1991 • 32 citations

Glucocorticoid receptor maps to the distal long arm of chromosome 5

1988 • 26 citations

Tyrosine hydroxylase maps to the short arm of chromosome 11 proximal to the insulin and HRAS1 loci

1988 • 18 citations

Progress towards completing the human linkage map

1991 • 7 citations

Linkage analysis of Schizophrenia: Challenges and promise

1991 • 7 citations

The current status of linkage studies in schizophrenia.

1991 • 6 citations

1989 Allen Award address: the American Society of Human Genetics annual meeting, Baltimore.

1990 • 5 citations