Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes

1980 • 648 citations

Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone.

1984 • 252 citations

Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila.

1986 • 173 citations

Interaction of the legionnaires' disease bacterium (Legionella pneumophila) with human phagocytes. II. Antibody promotes binding of L. pneumophila to monocytes but does not inhibit intracellular multiplication.

1981 • 169 citations

Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes.

1987 • 169 citations

Studies on hypersensitivity. II. Delayed hypersensitivity to denatured proteins in guinea pigs.

1959 • 163 citations

Interaction of the legionnaires' disease bacterium (legionella pneumophila) with human phagocytes. I. L. pneumophila resists killing by polymorphonuclearleukocytes, antibody, and complement

1981 • 162 citations

Activated human monocytes inhibit the intracellular multiplication of legionnaires' disease bacteria

1981 • 159 citations

Cell-mediated Immunity in Legionnaires' Disease

1983 • 127 citations

Reactivity of Serum from Patients with Suspected Legionellosis Against 29 Antigens of Legionellaceae and Legionella-Like Organisms by Indirect Immunofluorescence Assay

1983 • 123 citations

EXPERIMENTAL TRANSMISSION OF LEGIONNAIRES' DISEASE BY EXPOSURE TO AEROSOLS OF LEGIONELLA PNEUMOPHILA

1981 • 117 citations

Dose-Response of Guinea Pigs Experimentally Infected with Aerosols of Legionella pneumophila

1980 • 105 citations

The Kinetics of Early Inflammatory Events During Experimental Pneumonia Due to Legionella pneumophila in Guinea Pigs

1983 • 75 citations

Purification and characterization of an extracellular protease of Legionella pneumophila

1986 • 74 citations

IMMUNE RESPONSES AGAINST NATIVE AND CHEMICALLY MODIFIED ALBUMINS IN MICE

1972 • 74 citations

Electron microscopic examination of the inflammatory response to Legionella pneumophila in guinea pigs.

1982 • 65 citations

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens.

1987 • 62 citations

Biological activity of protein antigens isolated from Mycobacterium tuberculosis culture filtrate

1988 • 60 citations

Immunogenic properties of modified antigen E. I. Presence of specific determinants for T cells in denatured antigen and polypeptide chains.

1974 • 58 citations

T cell recognition of listeriolysin O is induced during infection with Listeria monocytogenes.

1987 • 57 citations

Legionnaires' pneumonia after aerosol exposure in guinea pigs and rats.

1982 • 52 citations