3-Methyladenine DNA glycosylase-deficient Aag null mice display unexpected bone marrow alkylation resistance.
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References (25)
DNA Repair and Mutagenesis
2006 • 4,725 citations
Passing the baton in base excision repair.
2000 • 338 citations
Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
1986 • 277 citations
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase
1997 • 232 citations
Risk of Acute Nonlymphocytic Leukemia and Preleukemia in Patients Treated with Cyclophosphamide for Non-Hodgkin's Lymphomas
1985 • 210 citations
3-methyladenine DNA glycosylases: structure, function, and biological importance
1999 • 194 citations
Generation of a strong mutator phenotype in yeast by imbalanced base excision repair
1998 • 189 citations
Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing.
1996 • 186 citations
In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells.
1993 • 177 citations
DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents
1999 • 146 citations
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase
1991 • 142 citations
Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.
1991 • 132 citations
Lessons learned from structural results on uracil-DNA glycosylase
2000 • 127 citations
ACCELERATED PAPER: Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent
1996 • 116 citations
Alkylpurine–DNA–N-Glycosylase Knockout Mice Show Increased Susceptibility to Induction of Mutations by Methyl Methanesulfonate
1998 • 112 citations
Comparison of Acridine Orange and Giemsa stains in several mouse bone marrow micronucleus assays—including a triple dose study
1989 • 96 citations
Contribution of Base Excision Repair, Nucleotide Excision Repair, and DNA Recombination to Alkylation Resistance of the Fission Yeast Schizosaccharomyces pombe
2000 • 95 citations
The suicidal DNA repalr methyltransferases of microbes
1992 • 94 citations
Measurement of Nucleic Acid Concentrations Using the DyNA Quant™ and the GeneQuant™
1997 • 76 citations
Acute nonlymphocytic leukemia, preleukemia, and solid tumors following intensive chemotherapy of small cell carcinoma of the lung
1985 • 74 citations
Cloning and characterization of a mouse 3-methyladenine/7-methl-guanine/-methylguanine DNA glycosylase cDNA whose gene maps to chromosme 11
1993 • 67 citations
Imbalanced Base Excision Repair Increases Spontaneous Mutation and Alkylation Sensitivity in Escherichia coli
1999 • 67 citations
Mammalian 3-methyladenine DNA glycosylase protects against the toxicity and clastogenicity of certain chemotherapeutic DNA cross-linking agents.
1998 • 60 citations
Groove- and sequence-selective alkylation of DNA by sulfonate esters tethered to lexitropsins
1993 • 60 citations
DNA polymerase mutagenic bypass and proofreading of endogenous DNA lesions
1999 • 19 citations