Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol.

Impaired rat sciatic nerve sodium-potassium adenosine triphosphatase in acute streptozocin diabetes and its correction by dietary myo-inositol supplementation.

1983 • 246 citations

Prevention of defects of axonal transport and nerve conduction velocity by oral administration of myo-inositol or an aldose reductase inhibitor in streptozotocin-diabetic rats

1983 • 215 citations

Glucose-induced Alterations in Nerve Metabolism: Current Perspective on the Pathogenesis of Diabetic Neuropathy and Future Directions for Research and Therapy

1985 • 196 citations

Polyol Pathway Activity and Myo-Inositol Metabolism: A Suggested Relationship in the Pathogenesis of Diabetic Neuropathy

1983 • 183 citations

Action of Sorbinil in Diabetic Peripheral Nerve: Relationship of Polyol (Sorbitol) Pathway Inhibition to a myo-Inositol-mediated Defect in Sodium-Potassium ATPase Activity

1984 • 178 citations

POLYOL ACCUMULATIONS IN NERVOUS TISSUE OF RATS WITH EXPERIMENTAL DIABETES AND GALACTOSAEMIA *

1967 • 166 citations

Axo-glial dysjunction. A novel structural lesion that accounts for poorly reversible slowing of nerve conduction in the spontaneously diabetic bio-breeding rat.

1986 • 166 citations

Sodium- and energy-dependent uptake of myo-inositol by rabbit peripheral nerve. Competitive inhibition by glucose and lack of an insulin effect.

1982 • 146 citations

Changes in nodal function in nerve fibres of the spontaneously diabetic BB‐Wistar rat: Potential clamp analysis

1981 • 143 citations

Diminished ouabain-sensitive, sodium-potassium ATPase activity in sciatic nerves of rats with streptozotocin-induced diabetes

1976 • 135 citations

Reversible diabetic nerve dysfunction: Structural correlates to electrophysiological abnormalities

1985 • 129 citations

Immunocytochemical localization of the sodium, potassium activated ATPase in knifefish brain

1977 • 117 citations

Nerve Na+-K+-ATPase, conduction, and myo-inositol in the insulin-deficient BB rat

1984 • 111 citations

Free and lipid inositol, sorbitol and sugars in sciatic nerve obtained post-mortem from diabetic patients and control subjects

1983 • 110 citations

Protein Kinase C Agonists Acutely Normalize Decreased Ouabain-inhibitable Respiration in Diabetic Rabbit Nerve: Implications for (Na,K)-ATPase Regulation and Diabetic Complications

1986 • 109 citations

Immunohistochemical Localization of Aldose Reductase: I. Enzyme Purification and Antibody Preparation—Localization in Peripheral Nerve, Artery, and Testis

1980 • 95 citations

Significance of Tissue myo -Inositol Concentrations in Metabolic Regulation in Nerve

1982 • 87 citations

Cytochemical localization of ouabain-sensitive, K+-dependent p-nitro-phenylphosphatase (transport ATPase) in the mouse central and peripheral nervous systems

1982 • 76 citations

Immunocytochemical Localization of (Na⁺,K⁺)‐ATPase in the Goldfish Optic Nerve

1981 • 76 citations

Sorbitol, inositol and nerve conduction in diabetes

1983 • 68 citations

Action of sorbinil in diabetic peripheral nerve. Relationship of polyol (sorbitol) pathway inhibition to a myo-inositol-mediated defect in sodium-potassium ATPase activity

1984 • 65 citations

Impaired energy utilization and Na-K-ATPase in diabetic peripheral nerve

1984 • 64 citations

Immunohistochemical localization of aldose reductase. I. Enzyme purification and antibody preparation--localization in peripheral nerve, artery, and testis

1980 • 47 citations

FUNCTIONAL ASPECTS AND PATHOGENETIC CONSIDERATIONS OF THE NEUROPATHY IN THE SPONTANEOUSLY DIABETIC BB‐WISTAR RAT

1981 • 42 citations

CAN THE BB‐RAT HELP TO UNRAVEL DIABETIC NEUROPATHY?

1985 • 38 citations

Protein kinase C agonists acutely normalize decreased ouabain-inhibitable respiration in diabetic rabbit nerve. Implications for (Na,K)-ATPase regulation and diabetic complications

1986 • 33 citations

A new simple preparation method for NaK-ATPase-rich membrane fragments

1981 • 30 citations

Nodal function of pathological nerve fibers

1983 • 15 citations

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