Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis.

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries

1986 • 2,422 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

1989 • 1,625 citations

Flow-induced release of endothelium-derived relaxing factor

1986 • 1,379 citations

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease.

1990 • 1,190 citations

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

1987 • 1,182 citations

Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity.

1992 • 1,021 citations

Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.

1991 • 1,010 citations

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

1989 • 862 citations

Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin

1983 • 855 citations

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.

1992 • 822 citations

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1991 • 813 citations

Endothelium‐dependent hyperpolarization of canine coronary smooth muscle

1988 • 785 citations

Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension.

1993 • 707 citations

The Effect of Atherosclerosis on the Vasomotor Response of Coronary Arteries to Mental Stress

1991 • 602 citations

Evidence of Impaired Endothelium-Dependent Coronary Vasodilatation in Patients with Angina Pectoris and Normal Coronary Angiograms

1993 • 567 citations

Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis.

1991 • 531 citations

Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta.

1990 • 527 citations

Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits.

1994 • 501 citations

Atherosclerosis or lipoprotein-induced endothelial dysfunction. Potential mechanisms underlying reduction in EDRF/nitric oxide activity.

1992 • 457 citations

Control of regional blood flow by endothelium-derived nitric oxide.

1990 • 447 citations

Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries.

1988 • 422 citations

Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans.

1989 • 421 citations

Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans.

1993 • 397 citations

Microvascular distribution of coronary vascular resistance in beating left ventricle

1986 • 374 citations

The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients.

1993 • 369 citations

Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise.

1989 • 368 citations

Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition.

1984 • 367 citations

Impaired coronary blood flow response to acetylcholine in patients with coronary risk factors and proximal atherosclerotic lesions.

1993 • 357 citations

Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery.

1982 • 345 citations

Flow-dependent coronary artery dilatation in humans.

1989 • 333 citations

Responses of angiographically normal human coronary arteries to intracoronary injection of acetylcholine by age and segment. Possible role of early coronary atherosclerosis.

1990 • 324 citations

Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation.

1994 • 296 citations

Nitric oxide synthesized from L‐arginine regulates vascular tone in the coronary circulation of the rabbit

1989 • 279 citations

Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis.

1994 • 264 citations

Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. PGH2 does not contribute to impaired endothelium-dependent relaxation.

1994 • 255 citations

Endothelial dysfunction in patients with chest pain and normal coronary arteries.

1992 • 234 citations

Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans.

1993 • 233 citations

Endothelium-dependent vascular relaxation is abnormal in the coronary microcirculation of atherosclerotic primates.

1990 • 232 citations

Direct vasoconstriction and endothelium-dependent vasodilation. Mechanisms of acetylcholine effects on coronary flow and arterial diameter in patients with nonstenotic coronary arteries.

1989 • 204 citations

Endogenous nitric oxide protects against platelet aggregation and cyclic flow variations in stenosed and endothelium-injured arteries.

1992 • 200 citations

Effects of inhibition of nitric oxide formation on basal vasomotion and endothelium-dependent responses of the coronary arteries in awake dogs.

1991 • 199 citations

Paradoxical narrowing of atherosclerotic coronary arteries induced by increases in heart rate.

1990 • 190 citations

Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits

1989 • 154 citations

Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans

1994 • 144 citations

Videomicroscopic demonstration of defective cholinergic arteriolar vasodilation in atherosclerotic rabbit.

1988 • 122 citations

Effects of atherosclerosis on the coronary microcirculation

1990 • 110 citations

Contribution of nitric oxide to dilation of resistance coronary vessels in conscious dogs

1992 • 107 citations

Importance of endothelium-derived nitric oxide in porcine coronary resistance arteries

1991 • 98 citations

Response of angiographically normal and atherosclerotic left anterior descending coronary arteries to acetylcholine

1990 • 91 citations

Nitric oxide modulates epicardial coronary basal vasomotor tone in awake dogs

1990 • 86 citations

Detection of coronary collateral flow by a Doppler-tipped guide wire during coronary angioplasty

1991 • 74 citations

Different endothelial mechanisms involved in coronary responses to known vasodilators

1992 • 61 citations

N‐nitro <scp>l</scp>‐arginine causes coronary vasoconstriction and inhibits endothelium‐dependent vasodilatation in anaesthetized greyhounds

1991 • 50 citations

Effect of an arginine analogue on acetylcholine-induced coronary microvascular dilatation in dogs

1991 • 47 citations

Endothelium-mediated regulation of coronary tone

1991 • 34 citations

Endothelium-Derived Nitric Oxide as a Mediator of Acetylcholine-Induced Coronary Vasodilation in Dogs

1991 • 24 citations