Nitrite as a Substrate and Inhibitor of Myeloperoxidase

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

1998 • 1,494 citations

Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry

1994 • 1,138 citations

Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite

1997 • 778 citations

Interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide. Inactivation of the enzyme

1975 • 777 citations

Myeloperoxidase: a key regulator of neutrophil oxidant production

1997 • 641 citations

Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways.

1993 • 616 citations

Inflammation: Basic Principles and Clinical Correlates

2000 • 616 citations

Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

1994 • 599 citations

Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro

1999 • 492 citations

Formation of Nitrating and Chlorinating Species by Reaction of Nitrite with Hypochlorous Acid

1996 • 440 citations

Thiocyanate and chloride as competing substrates for myeloperoxidase

1997 • 392 citations

The reaction of NO· with O2·− and HO2·−: A pulse radiolysis study

1995 • 389 citations

The basic chemistry of nitrogen monoxide and peroxynitrite

1998 • 345 citations

Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.

1993 • 345 citations

Reactions of nitrogen dioxide in aqueous model systems: Oxidation of tyrosine units in peptides and proteins

1985 • 333 citations

Kinetics and Mechanisms of Hypochlorous Acid Reactions

1995 • 330 citations

Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils

1995 • 321 citations

Myeloperoxidase and Horseradish Peroxidase Catalyze Tyrosine Nitration in Proteins from Nitrite and Hydrogen Peroxide

1998 • 311 citations

[53] Assays for the chlorination activity of myeloperoxidase

1994 • 260 citations

The separation of o-phthalaldehyde derivatives of amino acids by reversed-phase chromatography on octylsilica columns

1986 • 200 citations

A Rapid and Simple Method for the Measurement of Nitrite and Nitrate in Plasma by High Performance Capillary Electrophoresis

1994 • 198 citations

Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs

1991 • 187 citations

Neutrophils convert tyrosyl residues in albumin to chlorotyrosine

1996 • 186 citations

Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid

1988 • 177 citations

Lack of Tyrosine Nitration by Peroxynitrite Generated at Physiological pH

1998 • 167 citations

Myeloperoxidase of the leukocyte of normal blood. I. Reaction of myeloperoxidase with hydrogen peroxide

1970 • 145 citations

Measurement of Nitrite and Nitrate in Biological Fluids by Gas Chromatography–Mass Spectrometry and by the Griess Assay: Problems with the Griess Assay—Solutions by Gas Chromatography–Mass Spectrometry

1997 • 144 citations

The superoxide radical reacts with tyrosine-derived phenoxyl radicals by addition rather than by electron transfer

1993 • 137 citations

Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: Sensitive and quantitative assays for oxidized amino acids in proteins and tissues

1999 • 95 citations

Superoxide is an antagonist of anti-inflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase

1993 • 93 citations

Oxidative Modification and Nitration of Human Low-Density Lipoproteins by the Reaction of Hypochlorous Acid with Nitrite

1997 • 92 citations

Relative Chlorinating, Nitrating, and Oxidizing Capabilities of Neutrophils Determined with Phagocytosable Probes

1997 • 83 citations

Electron Paramagnetic Resonance Detection of Free Tyrosyl Radical Generated by Myeloperoxidase, Lactoperoxidase, and Horseradish Peroxidase

1998 • 80 citations

Myeloperoxidase-Catalyzed Oxidation of Tyrosine

1999 • 54 citations

Pulse-radiolysis study of the reaction of nitric oxide with superoxide

1995 • 53 citations

Spectral properties of myeloperoxidase Compounds II and III

1987 • 51 citations

Detection of 3-chlorotyrosine in proteins exposed to neutrophil oxidants

1999 • 27 citations

Superoxide generation by the human polymorphonuclear leukocyte in response to latex beads

1992 • 15 citations