Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

2003 • 10,537 citations

CD4+CD25+ Immunoregulatory T Cells

2002 • 1,434 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

Prevention of Arthritis by Interleukin 10–producing B Cells

2003 • 816 citations

The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice

2003 • 766 citations

Following a diabetogenic T cell from genesis through pathogenesis

1993 • 708 citations

Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry

1998 • 669 citations

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

1996 • 581 citations

AN IMPROVED METHOD FOR ISOLATION OF MOUSE PANCREATIC ISLETS

1985 • 548 citations

B Lymphocytes Are Critical Antigen-Presenting Cells for the Initiation of T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice

1998 • 454 citations

CD4+CD25+ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

2004 • 443 citations

Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice

1997 • 359 citations

Checkpoints in the progression of autoimmune disease: lessons from diabetes models.

1996 • 340 citations

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1994 • 309 citations

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Regulates the Unfolding of Autoimmune Diabetes

1998 • 295 citations

Development of Type 1 Diabetes despite Severe Hereditary B-Cell Deficiency

2001 • 251 citations

Pancreatic islet-specific T-cell clones from nonobese diabetic mice.

1989 • 246 citations

Genetic Absence of γ-Interferon Delays but Does Not Prevent Diabetes in NOD Mice

1996 • 244 citations

Effect of Cyclophosphamide on Immunological Control Mechanisms

1982 • 236 citations

Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide

1984 • 220 citations

Interferon-γ impacts at multiple points during the progression of autoimmune diabetes

1997 • 201 citations

Anti‐suppressor effect of cyclophosphamide on the development of spontaneous diabetes in nod mice

1988 • 199 citations

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

2002 • 195 citations

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

2001 • 166 citations

Genetic Control of Diabetes Progression

1997 • 148 citations

Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice.

2000 • 124 citations

Cyclophosphamide treatment of female non-obese diabetic mice causes enhanced expression of inducible nitric oxide synthase and interferon-gamma, but not of interleukin-4

1994 • 110 citations

Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells

2000 • 102 citations

Mechanism Underlying Counterregulation of Autoimmune Diabetes by IL-4

1997 • 100 citations

Protection of Nonobese Diabetic Mice from Diabetes by Gene(s) Closely Linked to IFN-γ Receptor Loci

2000 • 99 citations

Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice

1996 • 86 citations

Cellular and molecular changes accompanying the progression from insulitis to diabetes

1999 • 85 citations

A Reg Family Protein Is Overexpressed in Islets From a Patient With New-Onset Type 1 Diabetes and Acts as T-Cell Autoantigen in NOD Mice

2002 • 81 citations

Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein

1999 • 78 citations

Regulation of Diabetes Development by Regulatory T Cells in Pancreatic Islet Antigen-Specific TCR Transgenic Nonobese Diabetic Mice

2002 • 70 citations

Pancreatic Regenerating Gene Overexpression in the Nonobese Diabetic Mouse During Active Diabetogenesis

1996 • 55 citations

Specific reg II gene overexpression in the non‐obese diabetic mouse pancreas during active diabetogenesis

1997 • 33 citations

Overexpression of the reg Gene In Non-obese Diabetic Mouse Pancreas During Active Diabetogenesis Is Restricted to Exocrine Tissue

2000 • 25 citations

The Microbial Product Lipopolysaccharide Confers Diabetogenic Potential on the T Cell Repertoire of BDC2.5/NOD Mice: Implications for the Etiology of Autoimmune Diabetes

2000 • 24 citations

Disease resistant, NOD-related strains reveal checkpoints of immunoregulation in the pancreas

2001 • 22 citations

Increased Expression of a Regenerating (reg) Gene Protein in Neonatal Rat Pancreas Treated with Streptozotocin.

1995 • 16 citations

Pancreatic regenerating gene overexpression in the nonobese diabetic mouse during active diabetogenesis

1996 • 15 citations

The organization of lymphoid tissue in relation to function.

1977 • 6 citations