Expression of cell cycle-dependent genes in young and senescent WI-38 fibroblasts.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

Cellular senescence and DNA synthesis

1973 • 537 citations

Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

1984 • 524 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

Nucleotide sequence of cloned cDNA of human c-myc oncogene

1983 • 316 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

Expression of a Cellular Oncogene During Liver Regeneration

1983 • 281 citations

Coordinate regulation of multiple histone mRNAs during the cell cycle in HeLa cells

1983 • 278 citations

α-Skeletal and α-Cardiac Actin Genes Are Coexpressed in Adult Human Skeletal Muscle and Heart

1983 • 237 citations

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells.

1985 • 227 citations

Growth-related changes in specific mRNAs of cultured mouse cells.

1983 • 209 citations

Isolation of cloned cDNA encoding mammalian ornithine decarboxylase.

1984 • 206 citations

Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells.

1984 • 205 citations

Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver.

1984 • 203 citations

Cell-cycle-specific cDNAs from mammalian cells temperature sensitive for growth.

1984 • 198 citations

Regulation of histone mRNA production and stability in serum-stimulated mouse 3T6 fibroblasts.

1983 • 186 citations

Expression of cell-cycle-dependent genes in phytohemagglutinin-stimulated human lymphocytes.

1985 • 149 citations

Regulation of actin mRNA levels and translation responds to changes in cell configuration.

1983 • 148 citations

Characterization of the cell cycle of cultured human diploid cells: Effects of aging and hydrocortisone

1977 • 137 citations

Transcriptional Activation and Subsequent Control of the Human Heat Shock Gene During Adenovirus Infection

1983 • 131 citations

Comparative heterokaryon study of cellular senescence and the serum-deprived state

1980 • 92 citations

Functional organization of the Harvey murine sarcoma virus genome

1980 • 91 citations

Entry into S phase is inhibited in two immortal cell lines fused to senescent human diploid cells

1979 • 91 citations

Expression of thymidine kinase and dihydrofolate reductase genes in mammalian ts mutants of the cell cycle.

1985 • 86 citations

Regulation of Histone mRNA Production and Stability in Serum-Stimulated Mouse 3T6 Fibroblasts

1983 • 85 citations

Adenovirus type 2 activates cell cycle-dependent genes that are a subset of those activated by serum.

1985 • 82 citations

Use of a Cell Cycle Mutant to Delineate the Critical Period for the Control of Histone mRNA Levels in the Mammalian Cell Cycle

1984 • 66 citations

c-Ha-ras-1 proto-oncogene amplification and overexpression during the limited replicative life span of normal human fibroblasts.

1985 • 60 citations

Thymidine triphosphate synthesis in senescent WI38 cells

1983 • 58 citations

Analysis of recombinant DNA clones specific for the murine p53 cellular tumor antigen.

1983 • 56 citations

Expression of histone genes in a G1-specific temperature-sensitive mutant of the cell cycle

1984 • 53 citations

Human Thymidine Kinase Gene: Molecular Cloning and Nucleotide Sequence of a cDNA Expressible in Mammalian Cells

1984 • 45 citations

Regulated Transcription of c-Ki-ras and c-myc During Compensatory Growth of Rat Liver

1984 • 42 citations

Induction of DNA polymerase α in senescent cultures of normal and Werner's syndrome cultured skin fibroblasts

1985 • 29 citations

Adenovirus Type 2 Activates Cell Cycle-Dependent Genes That Are a Subset of Those Activated by Serum

1985 • 25 citations

Cell cycle dependent genes inducible by different mitogens in cells from different species

1986 • 24 citations

Transcriptional regulation of a tumor promoter and mitogen-inducible gene in human lymphocytes.

1984 • 21 citations

Approaches to mapping the temporal events in the cell cycle using conditional lethal mutants

1978 • 11 citations

Transcriptional Regulation of a Tumor Promoter and Mitogen-Inducible Gene in Human Lymphocytes

1984 • 9 citations

Human diploid fibroblasts (HDF) can induce DNA synthesis in cycling HDF but not in quiescent HDF or senescent HDF*1

1983 • 6 citations